Associate Professor and OCTRU Lead Statistician
- Senior Medical Statistician
Expert in statistics and clinical trial methodology
I am an experienced senior statistician working with medical professionals to design, achieve grant funding, conduct, analyse and report randomised clinical trials. I oversee an expanding group of medical statisticians at the Oxford Clinical Trials Research Unit – embedded in the Centre for Statistics in Medicine (CSM) – where I provide statistical management and input into all five therapeutic streams: musculoskeletal and rheumatology, rehabilitation and trauma, surgical interventions and oncology. I also teach short courses, workshops and hour-long training bites on how to conduct a trial.
My expertise range from simple standard two-arm parallel group trials to complex multi-arm trials, factorial trials and trials within a cohort. I have worked on all aspects of intervention development, from early phase and pilot/feasibility studies to phase III pragmatic randomised trials, investigating drug and medical device interventions as well as complex rehabilitation and surgical interventions.
I provide independent statistical expertise to external bodies such as a NICE Technology Appraisal Committee, Data and Safety Monitoring Committees and Trial Steering Committees. I am an Associate Editor of Trials and provide independent peer review for grant applications, final study reports and journal publications. I am a member of the UKCRC Statistics Group and the NIHR Statistics Group.
My career started in medical statistics in Liverpool at the Congenital Malformations Registry and then moved to Oxford to explore the geographical distribution of childhood cancers around nuclear installations. I joined CSM as an oncology trial statistician in 2007 and was appointed OCTRU Lead Statistician in 2013.
In my spare time, I am an obsessive patchwork and quilter, and enjoy reading, walking, geology, theatre trips and holidays to mountains and islands.