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Senior Research Scientiist
- Anaesthesia and Pain Analgesia Imaging Neuroscience Group
- Oxford Persisting Post-Operative Pain Study (OxPPOPS)
I have a broad range of research interests in neuroimaging of anaesthesia, pain and sleep. I use multi-modal neuroimaging techniques, such as combined electrocephalography (EEG) and magnetic resonance imaging (MRI), to observe the changes in the brain’s activity and connectivity associated with altered states of consciousness, particularly general anaesthesia and sleep.
I am principal investigator of the Oxford Persisting Post-Operative Pain Study (OxPPOPS). OxPPOPS is a major clinical trial to identify the incidence and predictive factors for development of chronic pain after surgery and its impact on quality of life.
Predictive factors under investigation are psychological, anaesthetic, surgical, genetic and hormonal factors as well as those relating to post-operative analgesic management and sleep. Identification of the variables that predict the development of persistent post-operative pain will allow interventions in ‘at-risk’ patients to be implemented.