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High Intensity Focused Ultrasound

Professor David Cranston talks about and demonstrates High Intensity Focused Ultrasound.

David Cranston

Associate Professor of Surgery

  • Consultant Urological Surgeon

I trained in Bristol and worked in Exeter and Bath before coming to Oxford in 1983 to do research in renal transplantation under the direction of Professor Sir Peter Morris. I was awarded my DPhil in 1986 and after a clinical lecturer post in urology and transplantation was appointed consultant urological and transplant surgeon in 1991. My special interest is in renal cancer and the urological complications of transplantation with a national referral for some patients needing complex renal cancer surgery. 

In 1992, I set up a research programme with Professor Adrian Harris, Director of the Cancer Research Unit in Oxford, and have co-supervised many research students who have carried out work in investigating bladder and kidney cancer. Several have won international awards for their work.

I have been clinical director of the High Intensity Focused Ultrasound (HIFU) unit since 2002.

I am author of 18 book chapters and over 100 peer reviewed publications.

High Intensity Focused Ultrasound is a novel way of treating solid tumours using a non-invasive technique to cause local ablation. HIFU also has applications in other areas such as delivering drug therapy and vascular occlusion, as well as the potential for enhancing anti-tumour immunity. Oxford has established itself as one of the leading international academic centres for clinical HIFU research. The research programme initially centred on the HIFU unit at the Churchill Hospital, and is now expanding into a number of laboratory based projects around the University in both the translational and clinical setting.

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Direct Entry Research Degrees