Fellows

Nora Bengoa-Vergniory

Liam Brown

Pablo Cespedes

'Inhibition of alpha-synuclein aggregation and glial activation as a therapeutic strategy for Parkinson’s disease'

'A computational framework for T cell trafficking and dynamics in anti-tumour immune responses'

'Studying the effects of citrullination on the dynamics of receptor-ligand pair interactions at the Immune Synapse'

PI: Richard Wade-Martins

 PI: Mark Coles, Eamonn Gaffney

Hebe Chen

Liliana Cifuentes

 Amy Cross

'Investigation of epigenetic and post-translational modifications in altered STAT3'

'Protein kinase C-θ and PD-1 as a therapeutic target in inflammatory arthritis'

'Combination therapy of low dose regulatory T cells and low dose IL-2 to prevent rejection in transplantation'

PI: Professor Holm Uhlig & Dr. Arian Laurence

PI: Graham Ogg, Peter Taylor, Mike Dustin

PI: Dr Joanna Hester & Dr Fadi Issa

Melanie Dunstan

Michael Fitzpatrick

Stefania Giussani

'Ultra low-dose IL-2 therapy in autoimmune diabetes'

'Use of unbiased T-cell receptor repertoire sequencing to identify novel T-cell subsets involved in coeliac disease and increase the accuracy of the diagnosis of gluten sensitivity'

'Investigation of T cell reactivity to alpha-synuclein in Parkinson's disease'

PI: John Todd, Claudia Monaco

PI: Elizabeth Soilleux, Paul Klennerman

Sarah Gooding

Tariq Khoyratty

Sarah Sasson

'Determining changes in clonal/sub clonal architecture and relation to immune marrow environment enabling tumour persistence/relapse in myeloma'

'Defining an early signature of neutrophil extracellular trap formative predictive of responses to PAD4/2 inhibitors in rheumatic patients'

'Checkpoint blockade-mediated autoimmune colitis as a model for gut immune homeostasis'

Hannah Chen

Thomas Layton

Heidi Olzscha

'Definition of new drug targets for fibrosis in Crohns'

'Single cell analysis of the fibrotic landscape in Dupuytren's Disease'

'Unravelling the role of E2F-1 citrullination in inflammatory disease'                                         

PI: Alison Simmons

PI: Jagdeep Nanchahal

PI: Nick La Thangue

Lynn Quek

'Clonal and Functional heterogeneity in AG221-treated IDH2 mutant Acute Myeloid Leukaemia'

PI: Paresh Vyas