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Patients with cirrhosis at increased risk of death from COVID-19, study finds

Coronavirus COVID-19 General Research

An international study led by researchers at Oxford University Hospitals NHS Foundation Trust has shown that patients with cirrhosis are at increased risk of dying as a result of COVID-19.

Hospitalised COVID-19 patients shown to be younger and healthier than flu patients

Coronavirus COVID-19 General Research

Patients hospitalised with COVID-19 were more likely male, younger and, in both the US and Spain, had fewer comorbidities and lower medication use than hospitalized influenza patients according to a recent study published recently by the Observational Health Data Sciences and Informatics (OHDSI) community.

Sites of early dysfunction in Parkinson's identified

General Research

A new collaborative study from the Oxford Parkinson’s Disease Centre has revealed that GABA transporters on astrocytes, the brain's lesser known yet critically important cells, support dopamine release and are sites of early dysfunction in parkinsonism.

New partnership with King Abdulaziz University aims to revolutionise drug discovery using artificial intelligence

General Research

The University of Oxford and King Abdulaziz University (KAU) have partnered to create a new Centre for Artificial Intelligence and Precision Medicine.

New trial to treat Covid-19 in care homes using anti-TNF drug begins

Clinical Trials Coronavirus COVID-19 Research

Researchers at the University of Oxford are starting a new study to explore the effectiveness of the anti-tumour necrosis factor (anti-TNF) drug adalimumab as a treatment for patients with COVID-19 in the community, especially care homes.

Ambitious Oxford initiative launched to address graduate under-representation

General

Oxford University and its colleges today announced a major new scholarship scheme for Black graduate students as part of a programme to transform its graduate population by creating more funding opportunities for under-represented groups.

Tiny brain “tweezers” could hold the key to treat Parkinson’s

General Research

A collaborative study led by Oxford Parkinson’s Disease Centre has shown that compounds known as molecular tweezers could become a promising disease modifying therapy for Parkinson’s.

Regular COVID-19 testing for groups most likely to spread the virus more efficient, cost-effective than random testing

Coronavirus COVID-19 General

As COVID-19 infections begin to rise again, a novel testing strategy proposed by researchers at the University of Oxford at the start of the pandemic has become urgent once again.

Comparison of five tests used to detect COVID-19 antibodies shows Siemens and Oxford assays met regulatory targets

Coronavirus COVID-19 Innovation Research

New research shows that, in a head-to-head comparison of five tests used to detect COVID-19 antibodies (known as ‘immunoassays’), an assay manufactured by Siemens and one developed by an academic partnership led by the University of Oxford had the most accurate results. The study is published in The Lancet Infectious Diseases.

Evaluation of LamPORE rapid tests for Covid-19 show high levels of diagnostic sensitivity

Coronavirus COVID-19 Research

Scientists from the University of Oxford’s Nuffield Department of Medicine have today published their evaluation of LamPORE, a novel diagnostic platform for detecting SARS-CoV-2 RNA. It combines loop-mediated isothermal amplification with nanopore sequencing. This technology has the potential to analyse thousands of samples per day on a single instrument.

Key discovery in Psoriatic Arthritis points way for developing targeted treatments

General Research

A new study has revealed psoriatic arthritis may be activated by the same trigger in different patients. Researchers from the University of Oxford and the Wellcome Sanger Institute identified high levels of a specific receptor in immune cells from psoriatic arthritis patients, giving the strongest evidence yet of a single cause for the disease.

PRINCIPLE Trial to strengthen Black, Asian and minority ethnic community participation

Coronavirus COVID-19 General Research

Professor Mahendra G Patel, University of Bradford, joins PRINCIPLE Trial as National Black, Asian and minority ethnic Community and Pharmacy Lead

Scientists discover what happens in our brains when we make educated guesses

General Research

Researchers have identified how cells in our brains work together to join up memories of separate experiences, allowing us to make educated guesses in everyday life.

More than half of Year 12 students report poor mental wellbeing since lockdown

Coronavirus COVID-19 Research

A school-based survey of students in Berkshire, Buckinghamshire, Gloucestershire, Oxfordshire and Wiltshire examined over 200 key factors in the lives and expectations of young people, aged 8-18 years, helping to shed light on mental health during lockdown.

New £4m study to advance our understanding of severe coronavirus infection

Coronavirus COVID-19 Research

The University of Liverpool is leading a major new international project to improve our understanding of severe coronavirus infection in humans, together with collaborators from the University of Oxford, Public Health England, the University of Bristol; A*STAR in Singapore; and King Fahd Medical City in Saudi Arabia.

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