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Globally the burden of gastrointestinal illness is greatest in low-income countries, where children under the age of five are disproportionately affected.

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In these countries, gastrointestinal illness is usually severe and one of the leading causes of death. Although most people recover from a gastrointestinal illness without the need for medical intervention in developed countries, some people go on to develop reactive arthritis (up to 65% in outbreak situations) and irritable bowel syndrome (up to 35%). These add a significant morbidity to the burden of gastrointestinal illnesses in these countries.

Read more (Nuffield Department of Primary Care Health Sciences)