A new study published in Nature reveals that the mechanical environment surrounding a tumour can cause cancer cells to change their behaviour, triggering a switch from rapid growth to a more invasive, drug-resistant state.
The brain\u2019s networks activate in structured cycles, according to a major new study led by the Department of Psychiatry at the University of Oxford.
An agreement has been reached for the acquisition of OrganOx, a pioneering University of Oxford spinout transforming kidney and liver transplantation, by Terumo Corporation, a global medical technology company headquartered in Tokyo, Japan, for US$1.5 billion. The transaction, which is subject to regulatory and other approvals, would be the largest acquisition of an Oxford University spinout to date, and one of the most significant venture capital exits in UK university spinout history.
A team of researchers at the University of Oxford have unveiled a pioneering \u2018microstent\u2019 which could revolutionise treatment for glaucoma, a common but debilitating condition. The study has been published in The Innovation, Cell Press.
Researchers in the Big Data Institute at the University of Oxford, together with MS experts from ten leading institutions across the world and drug developers from Novartis and Roche, have collaborated to develop an artificial intelligence (AI) model for reclassifying the progression of multiple sclerosis (MS). This model is based on the largest collection of clinical trial data (Novartis-Oxford MS dataset) from people living with MS.
A team led by scientists at the University of Oxford and the Leibniz-Forschungsinstitut f\u00fcr Molekulare Pharmakologie in Berlin has used fluorescent versions of next-generation diabetes and obesity drugs to reveal, for the first time, exactly which cells they target in the pancreas and brain.
A new study by Associate Professor Dennis Egger (Department of Economics and Centre for the Study of African Economies, University of Oxford) and researchers at the University of California, Berkeley reveals that giving unconditional cash transfers to pregnant women in rural Kenya significantly reduces infant and child mortality.
On 8 July 2025, researchers at the KEMRI-Wellcome Trust Research Programme began the Phase II trial of the ChAdOx1 RVF vaccine in Kilifi, Kenya\u2014the most advanced Rift Valley fever vaccine study in an outbreak-prone region. Led by Oxford University and funded by CEPI, this milestone brings us closer to a licensed vaccine for protecting lives and livelihoods.
Study led by Psaila Group uncovers previously unknown function of platelets as DNA \u2018vacuum cleaners\u2019 in the blood, with profound implications for cancer diagnosis and prenatal screening.
A multi-disciplinary study by KEMRI-Wellcome Trust, Harnessing Innovation in Global Health for Quality Care (HIGH-Q), has revealed how workforce issues influence the quality of care in newborn units. The research highlighted the effect of severe nurse staffing shortages in Kenyan hospitals as a major obstacle to providing quality care for newborns.
Overweight patients waiting for operations could safely use a particular type of weight-loss treatment to reduce the risk of surgical complications linked to their obesity, a new study reveals.
Women with obesity who participate in weight loss programmes before starting in vitro fertilisation (IVF) are 47% more likely to conceive naturally than those receiving minimal or no weight loss support, according to the most comprehensive systematic review of the evidence to date.
Researchers at NDM\u2019s Centre for Human Genetics have discovered that cell-free DNA builds up in the blood of patients with sepsis because of impaired liver clearance. These findings show that investigating cell-free DNA could be a powerful tool for monitoring what happens in the body during sepsis.
Continuing treatment with aromatase inhibitors (a type of hormone therapy) for another five years further reduces the risk of developing secondary breast cancer by over a quarter for certain women. These results from the Early Breast Cancer Trialists\u2019 Collaborative Group (EBCTCG), based at Oxford Population Health, are published in The Lancet.
In a collaborative new study, researchers have developed the first mathematically supported cellular map of lung tissue in idiopathic pulmonary fibrosis and uncovered key immune cell interactions that could explain why lungs fail to repair in this deadly disease with no known cure.
A new paper conducted by the Infectious Disease Data Observatory and the World Health Organization has revealed major gaps in research on noma, a severe and often fatal oral disease affecting children in low-resource settings. The review analysed 366 studies to provide a comprehensive foundation for future research and policy action.
A pioneering research centre aimed at achieving better mental health outcomes for children, young people and families will be established at the University of Oxford thanks to a \u00a327 million gift from The Paul Foundation.
Hosted by the Centre for Genomic Pathogen Surveillance at PSI, the new Centre will support efforts to tackle one of the most pressing global health challenges of our time - antimicrobial resistance.
Oxford researchers have unveiled new insights into the ongoing evolutionary battle between humans and the malaria parasite. The international team has discovered how the malaria parasite evades the immune system\u2014and how the human body fights back.
![\"Cancer](\"https://www.medsci.ox.ac.uk/news/new-research-shows-that-pressure-flips-the-switch-on-cancer-cells/responsive_image?ratio=r16x9&scale=w760\")
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