Researchers in the Department of Oncology have uncovered new insights into how FLASH radiation therapy kills cancer cells while minimising damage to healthy tissues. Published in Cell Death & Disease, the study shows the key role of iron levels in FLASH radiotherapy's tissue-sparing effect.
The MBRRACE-UK collaboration, co-led by Oxford Population Health\u2019s National Perinatal Epidemiology Unit, has today published the full Saving Lives, Improving Mothers\u2019 Care report on women who died during or up to a year after pregnancy between 2021 and 2023.
Oxford scientists build a connected, \u2018multi-organoid\u2019 platform that recreates immune recruitment to the heart, opening new avenues to probe disease and test therapies.
The Centre for Suicide Research investigates the extent, nature and causes of self-harm and suicide, with the aim of translating the findings into implications for prevention, treatment and support.
A major UK study, led by researchers at the University of Oxford\u2019s Nuffield Department of Primary Care Health Sciences, Oxford University Hospitals NHS Foundation Trust, the National Institute for Health and Care Research (NIHR) Oxford Biomedical Research Centre, and Oxford Cancer, has provided the most comprehensive analysis to date of a cancer diagnosis pathway for patients presenting with non-specific symptoms (NSS), such as unexplained weight loss or fatigue.
Evidence from the Million Women Study has shown that women who have hypertension (high blood pressure) in their 50s or 60s are at increased risk of developing vascular dementia in their 70s or 80s. The study is published in Alzheimer\u2019s and Dementia.
Long-term results from the largest randomised trial of stenting and surgery have shown that the procedures are equally protective against stroke resulting from carotid artery disease.
Luana Soares, Francis Szele and colleagues from Oncology (Eric O\u2019Neill), from Paediatrics (Mathew Wood) and from DPAG (Zoltan Molnar, Mootaz Salman), have identified Galectin-3 as a key regulator of neural development, establishing its contribution to brain growth.
Today, eleven researchers at the University of Oxford have been selected to receive prestigious European Research Council (ERC) Starting Grants, each worth \u20ac1.5 million for a period of up to five years.
Researchers have identified bioactive peptide sequences in PEPITEM molecules, and demonstrated the biological activity of the full PEPITEM molecule in counteracting key changes caused by osteoporosis.
Scientists at the University of Oxford, together with colleagues at Imperial College London and the University of Glasgow, have developed a new type of immunotherapy that could improve outcomes for infants and children with high-risk leukaemia.
The University of Oxford, through its strategic partnership with the Ellison Institute of Technology (EIT), has received research funding of \u00a3118m to launch an ambitious new programme of vaccine research.
Two new papers from scientists in the Nuffield Department of Medicine and other University of Oxford institutions have shown how the immune system reacts differently depending on the length of interval between vaccine doses.
The Kaiya Foundation has awarded one of its first major research grants, which will fund pioneering research into the fundamental cause of a high-risk leukaemia. The grant is being made to Dr Emily Neil and Professor Anindita Roy from the Childhood Leukaemia Research Group, based at the University of Oxford, in the hope that their discoveries will transform treatment approaches for sufferers through personalised medicine.
Teenagers who experience moderate or severe period pain are significantly more likely to develop chronic pain in adulthood \u2013 including pain beyond the pelvis \u2013 according to a major new study from the University of Oxford, funded by the Medical Research Foundation.
Researchers from the Centre for Evidence in Transplantation (CET), led by Associate Professor Simon Knight, have been awarded a prestigious five-year National Institute for Health Research (NIHR) Programme Grant for Applied Research (PGfAR). The project will develop and evaluate AI-driven clinical decision support tools to help clinicians make better-informed choices about kidney transplant offers.
A clinical trial led by researchers in the University of Oxford\u2019s Radcliffe Department of Medicine and Oxford Population Health, has found that while a structured weight-loss programme helped older adults with atrial fibrillation (AF) shed weight safely and sustainably, it did not improve their heart rhythm symptoms or reduce the need for further treatment.
A wearable electrocardiogram (ECG) patch increases diagnosis of a common heart rhythm disorder, according to a study by researchers from Nuffield Department of Primary Care Health Sciences and led by a team at Oxford Population Health.
Sinus surgery is more effective than antibiotics at treating chronic rhinosinusitis, according to a major clinical trial led by UCL, coordinated by the Oxford Clinical Trials Research Unit (OCTRU) and Surgical Intervention Trials Unit (SITU) at NDORMS, in collaboration with researchers across the UK.
![\"Iron](\"https://www.medsci.ox.ac.uk/news/new-study-shows-how-flash-radiotherapy-kills-cancer-cells-while-sparing-healthy-tissue/responsive_image?ratio=r16x9&scale=w760\")
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