Engineers and healthcare scientists from the University of Oxford and the University of Cape Town, South Africa, have come together to improve technologies for diagnosing disease and furthering our understanding of fundamental processes of disease. By advancing three-dimensional imaging of tissue at the microscopic scale, tissue-based analysis of changes in gene expression, and artificial intelligence methodologies, the team aims to generate new insights from tissue samples into health and disease.
Following the outbreak of Andes hantavirus disease on the cruise ship MV Hondius, UK universities and the UK Health Security Agency (UKHSA) have launched a new clinical study to characterise infection and disease associated with Andes hantavirus.
Researchers, clinicians, industry partners, bone cancer charities and patients recently gathered at St Catherine\u2019s College, University of Oxford, for the inaugural \u2018Oxford Workshop on Systems Biology and Therapeutic Approaches in Chondrosarcoma\u2019. The event brought together expertise across research and clinical care with the long-term aim to improve outcomes for patients with chondrosarcoma.
Scientists in Oxford have developed a faster way to identify the organisms causing bloodstream infections and to predict antibiotic resistance using rapid DNA sequencing, a move that could improve the care of sepsis patients in hospital and reduce unnecessary antibiotic use. Up to 245,000 people develop sepsis each year in the UK, and 48,000 die as a result.
The largest-ever study mapping genetic variants of HIV-1 around the world over the past 35 years shows that the regional distribution of different subtypes of the virus continues to evolve, posing a challenge to prevention and treatment efforts.
A major national study led by the University of Oxford to evaluate newborn screening for spinal muscular atrophy (SMA) has been funded by the National Institute for Health and Care Research (NIHR), marking a significant milestone towards the potential introduction of SMA screening across the UK.
Two research groups at the University of Oxford have been awarded funding through the prestigious International Cardiovascular Research Partnership Awards, to support high-quality international research collaborations that have the potential to accelerate progress towards improved understanding, prevention, diagnosis and treatment of cardiovascular disease.
A first-in-human pilot study, published in Nature Medicine, suggests that selectively removing a placenta-derived protein called soluble Fms-like tyrosine kinase 1 (sFlt-1) from the blood may be a safe and feasible way to help manage very preterm preeclampsia.
Poor mental health is an urgent issue in England.1 in 5 adults experience a common mental health problem. This impact is felt not only by individuals and families, but across society as a whole - in 2022, the Centre for Mental Health estimated that the economic and social costs of mental ill health in England was \u00a3300 billion a year - nearly double the annual NHS England budget.
A major international study published today in BMJ Public Health has found that a digitally enabled healthcare programme was associated with significant improvements in blood pressure control among people living with hypertension across sub-Saharan Africa.
The OpenBind consortium\u2019s first release of experimental data marks a milestone in efforts to improve how artificial intelligence (AI) is used in drug discovery.
Professor Andrew Sharott (Team leader) and Professor Laura Parkkinen (Co-Investigator) from Nuffield Department of Clinical Neurosciences (NDCN) have been selected for multi-year grants to join the Collaborative Research Network (CRN) an international, multidisciplinary, multi-institutional network working to address high-priority research questions about Parkinson's disease.
The Nuffield Department of Women's & Reproductive Health is proud to announce that it is now leading Tommy's National Centre for Miscarriage Research, alongside existing partners: the University of Birmingham, the University of Warwick, and Imperial College London.
The European Patent Office has announced that Professor Adrian Hill, Lakshmi Mittal Professor of Vaccinology and Director of the Jenner Institute at Oxford University, is one of three finalists in the \u2018Research\u2019 category of the European Inventor Award for his development of a vaccine against Malaria.
Researchers from the University of Oxford, the Stowers Institute for Medical Research, Helmholtz Munich, and the Technical University of Munich have developed a new artificial intelligence framework that helps uncover how cells make developmental decisions.
A large international study led by researchers at the University of Oxford and the University of Virginia (USA) has identified a new model for predicting outcomes for hypertrophic cardiomyopathy (HCM) \u2013 a heart condition that is the most frequent cause of sudden cardiac death in younger individuals.
Researchers from the Department of Oncology in collaboration with the Department of Chemistry have developed a promising new compound designed to reduce tumour hypoxia, a major cause of radiotherapy resistance.
On World Ovarian Cancer Day, we recognise the impact ovarian cancer has on women and families worldwide, and the urgent need for earlier diagnosis, improved treatment, and better survival outcomes. The day also highlights the importance of continued research to improve understanding of ovarian cancer biology, diagnosis, treatment, and patient outcomes.
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