PRINCIPLE Covid-19 treatments trial widens to under 50s and adds colchicine

Study reveals high number of persistent COVID-19

22 February 2024

A new study led by the University of Oxford has found that a high proportion of SARS-CoV-2 infections in the general population lead to persistent infections lasting a month or more. The findings have been published today in the journal Nature.

Single cell spatial analysis provides new insight into immune-pathology in Covid-19 lungs

9 November 2023

A Nature Communications study led by Professor Ling-Pei Ho’s group in the MRC Translational Immune Discovery Unit (TIDU) provides new insights into how immune cells interact in the lungs of patients with severe COVID-19.

RECOVERY trial expands to investigate treatments for influenza

31 October 2023

The RECOVERY trial, which discovered four effective treatments for COVID-19, has expanded to investigate treatments for influenza (flu).

Oxford launches new vaccine trial to enhance design of flu & COVID-19 vaccines

26 October 2023

This study will test the responses of cells in lymph nodes before and after immunisation with flu and COVID-19 vaccines and compare reactions in older and younger adults

Oxford to lead global collaboration to research and develop next-generation COVID-19 and flu vaccines

11 October 2023

Project headed by Oxford University’s Professor Teresa Lambe OBE (Calleva Head of Vaccinology and Immunology, Department of Paediatrics) and co-developer of the Oxford/AstraZeneca COVID-19 vaccine and Paul Klenerman (Sidney Truelove Professor, Nuffield Department of Medicine)

Longer-term organ abnormalities confirmed in some post-hospitalised COVID patients

25 September 2023

A study looking at the longer-term impact of COVID-19 has found that nearly a third of patients displayed abnormalities in multiple organs five months after infection, some of which have been shown through previous work to be evidence of tissue damage.

Young people’s mental health deteriorated at greater rate during the pandemic

25 September 2023

Young people’s mental health deteriorated during COVID-19, with higher levels of depression and social, emotional and behavioural difficulties than before the pandemic hit, a comprehensive new study has shown.

Evidence shows COVID-19 triggers sustained inflammatory gene expression

22 September 2023

In a study, recently published in Genomics Medicine, researchers from NDM’s Wellcome Centre for Human Genetics and the CAMS Oxford Institute investigated the long-term impact of COVID-19 on immune cells.

Study shows detrimental impact of Long Covid on the education and lives of children and young people

20 September 2023

New research from the Nuffield Department of Primary Care Health Sciences at the University of Oxford, and the universities of Stirling and Aberdeen funded by the National Institute for Health and Care Research (NIHR), has shone a spotlight on the profound effect Long Covid can have on children and young people’s school experience and wider lives.

Blood clots during COVID-19 may be a cause of ongoing cognitive problems

4 September 2023

High levels of two proteins at the time of COVID-19 have been found in patients who later experienced cognitive problems, including ‘brain fog’, giving a major clue as to one cause of their symptoms: blood clots.

COVID-19 measures reduced life-threatening invasive bacterial infections

28 July 2023

Containment measures introduced to prevent the spread of SARS-CoV-2 resulted in a sustained reduction in the transmission of certain bacteria that cause diseases such as meningitis, sepsis and pneumonia, according to a new study published in The Lancet Digital Health by the Invasive Respiratory Infection Surveillance (IRIS) Consortium.

The safety of GP prescribing in England was not adversely affected by the Covid-19 pandemic

19 May 2023

Researchers from the universities of Oxford and Nottingham have found that despite substantial disruption to primary care services, the safety of GP prescribing in England was largely unaffected by the Covid-19 pandemic.

Landmark antibody study to test immune responses against COVID-19

17 April 2023

Thousands of immunosuppressed people, including patients at Oxford University Hospitals (OUH), have the chance to take part in a landmark new study investigating which people are still at the greatest risk of COVID-19 infection after vaccination.

Trial investigating potential treatment for fatigue relief in people with long COVID reports results

17 April 2023

Researchers from the University of Oxford have reported findings from a Phase 2 clinical trial investigating the efficacy of an investigational treatment against long COVID fatigue. The study (reported in Lancet eClinical Medicine) found participants given the treatment, developed by US pharmaceutical company Axcella Therapeutics, reported feeling less fatigued than those given a placebo.

School closures may reduce COVID-19 transmission, but may also harm children's education and wellbeing

31 March 2023

Researchers at the University of Oxford have conducted a systematic overview of reviews to assess the impact of school closures during the COVID-19 pandemic.

NHS COVID-19 app saved estimated 10,000 lives in its first year, new research finds

22 February 2023

A team of experts at the Pandemic Sciences Institute at the University of Oxford and Department of Statistics at the University of Warwick estimate the NHS COVID-19 app prevented around 1 million cases, 44,000 hospitalisations and 9,600 deaths during its first year.

Study supports evidence ivermectin not effective to treat COVID-19

21 February 2023

High doses of the drug ivermectin, controversially recommended by some high-profile political and media figures during the COVID-19 pandemic, is ineffective at treating the COVID-19 virus, say University of Oxford-affiliated researchers in a study published today in eLife.

Coronavirus Vaccines Research and Development Roadmap launched

21 February 2023

The Coronavirus Vaccines Research and Development Roadmap is a comprehensive plan to galvanize a global effort to protect the world from this large and dangerous family of viruses.

COVID-19 is a leading cause of death in children and young people in the US

31 January 2023

A new study led by researchers at the University of Oxford’s Department of Computer Science has found that, between 2021 and 2022, COVID-19 was a leading cause of death in children and young people in the United States, ranking eighth overall. The results demonstrate that pharmaceutical and public health interventions should continue to be applied to limit the spread of the coronavirus and protect again severe disease in this age group.

COVID-19 increased public trust in science, new survey shows

26 January 2023

A survey of over 2000 British adults has found that public trust in science, particularly genetics, increased significantly during the pandemic. However, those with extremely negative attitudes towards science tend to have high self-belief in their own understanding despite low textbook knowledge.

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