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Potential new route to treatment for Cerebellar Ataxia

Research

Researchers from the teams of Andrea Németh (NDCN) and Esther Becker (DPAG) have published an important paper reporting dominant mutations that cause a new type of cerebellar ataxia, Spinocerebellar Ataxia type 44.

ECell based experiments characterise the function of the mutant receptors. Photo courtesy of Esther Becker.

Spinocerebellar ataxias are a group of diseases that are caused by degenerative changes in the cerebellum, a part of the brain important for movement control. There are many different types of spinocerebellar ataxia and each may have unique signs and symptoms. However, in general, all are characterised by problems with movement that tend to get worse over time.

Read more (Nuffield Department of Clinical Neurosciences website)

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