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Structure of a region of the conserved protein Seb1 from fission yeast

A new study from Lidia Vasilieva's group in the Department of Biochemistry in collaboration with researchers at the Division of Structural Biology at the University of Oxford (STRUBI) and the Max-Planck Institute for Biophysical Chemistry in Göttingen, Germany, sheds light on how a group of conserved proteins orchestrate transcription termination in eukaryotes.

The work, which is published in Nature Communications, also unexpectedly reveals that fission yeast and possibly other eukaryotes use a different mechanism from the model eukaryote budding yeast to regulate non-coding transcripts.

Read more (Department of Biochemistry website)