Cookies on this website
We use cookies to ensure that we give you the best experience on our website. If you click 'Continue' we'll assume that you are happy to receive all cookies and you won't see this message again. Click 'Find out more' for information on how to change your cookie settings.

A new study by Kennedy Institute's Professor Katja Simon, and colleagues published in Molecular Cell shows that spermidine, a naturally occurring metabolite found in most human cell types, boosts antibody production in both old mice and immune cells from the elderly.

The findings may offer an approach for improved vaccination strategies for older people who are less responsive to vaccines and more vulnerable to infection.

The team found that spermidine kick-starts the immune system through autophagy, a cellular recycling pathway that declines as cells age.

Read more (Kennedy Institute website)

Similar stories

New study finds that politicians typically enjoy longer lives than general populations

New data show politicians have a considerable survival advantage over general populations, based on information from 11 countries and over 57,500 politicians. In some countries this survival advantage is at the highest level for 150 years, and life expectancy at age 45 was found to be around seven years higher for politicians compared to general populations in certain countries.

Five ways the pandemic has affected routine medical care

Since the beginning of the pandemic, COVID has infected at least a third of the UK population and is estimated to have factored in the deaths of almost 200,000 people in the UK. But critically, COVID has also had a devastating impact on our healthcare systems. While this was expected, new evidence is beginning to reveal the scope of the issue – in particular the effects for people living with long-term health conditions.

Clinical trials for a malaria vaccine start in Mali and Indonesia

Sanaria Inc. announced that two new Phase 2 trials of its pioneering malaria vaccines have started. The first is in 6- to 10-year-old children living in Bancoumana, Mali, a malarious region of West Africa. The second is in Indonesian soldiers based in Sumatra, Indonesia. The soldiers will be deploying for six to nine months this coming August to an intensely malarious district in eastern Indonesia.

Researchers discover novel form of adaptation in the auditory system

Researchers in the Department of Physiology, Anatomy and Genetics (DPAG) have found that the auditory system adapts to the changing acoustics of reverberant environments by temporally shifting the inhibitory tuning of cortical neurons to remove reverberation.

20 minutes of daily exercise can keep teens' doctors away

Teenagers should exercise vigorously for at least 20 minutes per day to reap increased cardiorespiratory fitness (CRF), according to a cross-sectional study from the UK led by University of Oxford researchers.

Mechanism of expanding bacteria revealed

A new study published in Nature has identified a potential Achilles heel in the protective layers surrounding Gram-negative bacteria that could aid in the development of next-generation antibiotics.