The work on the Fanconi anaemia (FA) DNA repair pathway, from the labs of Dr. Martin Cohn in the Department of Biochemistry and Dr. Catherine Vénien-Bryan at the Pierre and Marie Curie University in Paris, has been published in Nature Communications. It explains how mutations in a crucial protein in the FA pathway disrupt the repair process, leading to devastating consequences for patients with the disorder.
Cryo-EM sheds light on how cells repair DNA damage
15 July 2016
A new study has revealed the sequence of key events in an important DNA damage pathway that is disrupted in patients with the cancer-prone Fanconi anaemia disorder.