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Research published in Science, the fruition of a collaborative project between Dr Uphoff in Professor David Sherratt's lab in the Department of Biochemistry and the lab of Professor Johan Paulsson at Harvard Medical School, has revealed that random variation in the DNA repair capacity of cells can lead to genetic variation. The work provides insight into how phenotypic variation can lead to genetic variation - a new twist on studies exploring the impact of variability in gene expression between cells.

Read more (Department of Biochemistry website)