Cookies on this website
We use cookies to ensure that we give you the best experience on our website. If you click 'Continue' we'll assume that you are happy to receive all cookies and you won't see this message again. Click 'Find out more' for information on how to change your cookie settings.

Antibiotics, not dirty hospitals, the main cause of C. difficile epidemic

  • Research

Restricting the use of a common antibiotic was more important than a high profile 'deep clean' of hospitals in massively reducing UK antibiotic resistant Clostridium difficile (C. diff) cases, a major new study has found.

Clostridium on gut lining Med. Mic. Sciences Cardiff Uni. Wellcome Images

The study concluded that overuse of antibiotics like ciprofloxacin led to the outbreak of severe diarrhoea caused by C. difficile that hit headlines from 2006 onwards. The outbreak was stopped by substantially reducing use of ciprofloxacin and related antibiotics.

Inappropriate use and widespread over prescribing of fluoroquinolone antibiotics such as ciprofloxacin in fact allowed C. difficile bugs that were resistant to the drug to thrive, because non-resistant bugs in the gut were killed off by the antibiotic, leaving the way clear for rapid growth of resistant C. difficile.

Read more (Oxford University Hospitals NHS Foundation Trust website)