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Pfizer is seeking proposals for renal disease target discovery utilising functional genomics technologies.

Submissions invited for novel functional genomics-driven target discovery efforts in renal disease, making use of highly relevant model systems and informative, high-dimensional readouts:

Experimental models

  • Organoids
  • Ex vivo tissue
  • Microphysiological systems
  • Primary cells
  • Complex cell mixtures
  • Other innovative and highly relevant model systems

Readouts

  • High-dimensional readouts that capture disease biology
  • Single-cell approaches
  • Transcriptomics and proteomics
  • High-content imaging assays

Technologies

  • Gene editing and other functional genomics methods
  • Functional genomics screening approaches at medium to large-scale

Disease/Biology focus

  • Chronic kidney disease
  • Diabetic nephropathy
  • Glomerular/tubular biology
  • Polycystic kidney disease

Out of scope

  • Rare kidney disease
  • Alport syndrome
  • Focal segmental glomerulosclerosis
  • IgA nephropathy

Submission deadline: 21 April 2023

For more information, please contact Nicole Le Grand, Business Partnerships Manager, Business Partnerships Office at nicole.legrand@medsci.ox.ac.uk.