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An internationally recognised centre of excellence for biomedical and clinical research and teaching
Study shows detrimental impact of Long Covid on the education and lives of children and young people
Coronavirus COVID-19 General Research
20 September 2023
New research from the Nuffield Department of Primary Care Health Sciences at the University of Oxford, and the universities of Stirling and Aberdeen funded by the National Institute for Health and Care Research (NIHR), has shone a spotlight on the profound effect Long Covid can have on children and young people’s school experience and wider lives.
Oxford and Liverpool scientists launch new vaccine trial for Middle East Respiratory Syndrome (MERS)
Clinical Trials General Research
19 September 2023
The UK trial is the next step in the development of a vaccine to protect people against MERS – a deadly viral illness with no current vaccines and the potential to cause a pandemic.
When it comes to starting a family, timing is everything
General Research
18 September 2023
The review, conducted jointly with researchers from Oxford University, the Royal Berkshire Hospital in Reading, and the Princess Anne Hospital in Southampton, included seven randomised controlled trials involving 2,464 women or couples who had been trying to conceive.
Continuing inequalities contribute to wide variation in rates of stillbirths and neonatal deaths across UK
General Research
18 September 2023
The MBRRACE-UK Collaboration, jointly led by Nuffield Department of Population Health’s National Perinatal Epidemiology Unit (NPEU) and the University of Leicester’s The Infant Mortality and Morbidity Studies (TIMMS) research group, has published a ‘State of the Nation’ report on perinatal deaths in babies born in the UK in 2021.
First volunteers receive vaccine for Crimean-Congo haemorrhagic fever in Oxford clinical trial
Clinical Trials General Research
13 September 2023
A University of Oxford study has administered a new vaccine against tick-borne virus Crimean-Congo haemorrhagic fever (CCHF) to volunteers for the first time. Launched on the 4th of August 2023, the clinical trial of the ChAdOx2 CCHF vaccine aims to confirm its safety and understand how individuals develop immunity following vaccination.
E-cigarettes, Varenicline and Cytisine found to be the most effective stop-smoking aids
General Research
13 September 2023
A comprehensive new analysis has found that nicotine e-cigarettes, varenicline and cytisine are the most effective options currently available for helping smokers quit long-term (going at least six months without smoking).
Polycystic ovary syndrome: losing weight can help but many sufferers are vulnerable to bad advice on social media
Research
12 September 2023
Polycystic ovarian syndrome (PCOS), a hormonal condition which affects how the ovaries work, is thought to affect 20% of women worldwide. Yet despite how common the condition is, and the serious effect it has on women’s health, researchers still aren’t completely sure what causes PCOS – let alone how best to manage and treat the condition.
Three new Oxford-BMS Translational Fellowships announced
General Innovation Research
11 September 2023
Poor metabolic health could increase risk of developing dementia later in life
General Research
8 September 2023
Researchers at Nuffield Department of Population Health have found that having poor metabolic health was related to an increased risk of developing dementia in a study of more than 176,000 individuals.
New study disentangles a long-standing link between inflammation and cancer progression
General Research
5 September 2023
A new study led by the Mead Group in the MRC Weatherall Institute of Molecular Medicine (Radcliffe Department of Medicine) has demonstrated a previously unknown effect of chronic inflammation on TP53-mutant haematopoietic stem cells.
Blood clots during COVID-19 may be a cause of ongoing cognitive problems
Coronavirus COVID-19 General Research
4 September 2023
High levels of two proteins at the time of COVID-19 have been found in patients who later experienced cognitive problems, including ‘brain fog’, giving a major clue as to one cause of their symptoms: blood clots.
Herman Waldmann awarded Royal Society Medal
Awards and Appointments General Research
30 August 2023
Professor Herman Waldmann FMedSci (Sir William Dunn School of Pathology) is one of four Oxford University researchers recognised today by the Royal Society.
New model predicts ten year breast cancer risk
General Research
25 August 2023
A team of researchers at the University of Oxford, led by the Nuffield Department of Primary Care Health Sciences, have developed a new model that reliably predicts a woman's likelihood of developing and then dying of breast cancer within a decade.
New study offers hope in early detection of oesophageal cancer
General Research
15 August 2023
Researchers at Oxford University's Nuffield Department of Primary Care Health Sciences have developed a new tool to predict people’s risks of getting oesophageal cancer in the next ten years.
Machine learning predicts SETD2 mutation status with unprecedented accuracy using DNA methylation
General Research
11 August 2023
In a pan-cancer analysis spanning 24 different cancer types, Department of Oncology researchers shed light on the critical role of SETD2 in tumourigenesis.
New Oxford study shows brief sleep therapy delivered by nurses improves insomnia
General Research
11 August 2023
Researchers from the University of Oxford have found that a brief form of cognitive behavioural therapy (CBT) for insomnia, delivered by nurses in GP surgeries, significantly improves sleep and quality of life compared to sleep hygiene alone.
Nanopore technology achieves breakthrough in protein variant detection
General Research
7 August 2023
A team of scientists led by the University of Oxford have achieved a significant breakthrough in detecting modifications on protein structures. The method, published in Nature Nanotechnology, employs innovative nanopore technology to identify structural variations at the single-molecule level, even deep within long protein chains.
Could removing fat from donor livers help save more lives?
General Research
3 August 2023
The liver transplant team at the Royal Free Hospital (RFH) has successfully recruited the first liver to be used in a revolutionary new study — looking at whether fat can be removed from donor livers to make them suitable for transplantation. The study is being run from the Nuffield Department of Surgical Sciences (NDS) at the University of Oxford.
Bespoke 3D lab models could unlock the secret to soft tissue joint diseases
General Research
3 August 2023
Research into the onset and progression of diseases affecting musculoskeletal soft tissues could be greatly advanced using novel 3D models say researchers in Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, in a review published in The Lancet Rheumatology.
Professor Sir Aziz Sheikh OBE appointed as next Nuffield Professor of Primary Care Health Sciences
Awards and Appointments General Research
31 July 2023
Professor Sir Aziz Sheikh has been appointed to succeed Professor Richard Hobbs CBE as Nuffield Professor of Primary Care Health Sciences and Head of Department from August 2024.