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An internationally recognised centre of excellence for biomedical and clinical research and teaching
Hospitalised COVID-19 patients shown to be younger and healthier than flu patients
Coronavirus COVID-19 General Research
6 October 2020
Patients hospitalised with COVID-19 were more likely male, younger and, in both the US and Spain, had fewer comorbidities and lower medication use than hospitalized influenza patients according to a recent study published recently by the Observational Health Data Sciences and Informatics (OHDSI) community.
Circadian rhythm: liver gene helps body keep working smoothly after late nights and midnight snacks
General Research
6 October 2020
Sites of early dysfunction in Parkinson's identified
General Research
2 October 2020
A new collaborative study from the Oxford Parkinson’s Disease Centre has revealed that GABA transporters on astrocytes, the brain's lesser known yet critically important cells, support dopamine release and are sites of early dysfunction in parkinsonism.
New partnership with King Abdulaziz University aims to revolutionise drug discovery using artificial intelligence
General Research
1 October 2020
The University of Oxford and King Abdulaziz University (KAU) have partnered to create a new Centre for Artificial Intelligence and Precision Medicine.
New trial to treat Covid-19 in care homes using anti-TNF drug begins
Clinical Trials Coronavirus COVID-19 Research
30 September 2020
Researchers at the University of Oxford are starting a new study to explore the effectiveness of the anti-tumour necrosis factor (anti-TNF) drug adalimumab as a treatment for patients with COVID-19 in the community, especially care homes.
Tiny brain “tweezers” could hold the key to treat Parkinson’s
General Research
29 September 2020
A collaborative study led by Oxford Parkinson’s Disease Centre has shown that compounds known as molecular tweezers could become a promising disease modifying therapy for Parkinson’s.
Comparison of five tests used to detect COVID-19 antibodies shows Siemens and Oxford assays met regulatory targets
Coronavirus COVID-19 Innovation Research
28 September 2020
New research shows that, in a head-to-head comparison of five tests used to detect COVID-19 antibodies (known as ‘immunoassays’), an assay manufactured by Siemens and one developed by an academic partnership led by the University of Oxford had the most accurate results. The study is published in The Lancet Infectious Diseases.
Parkinson’s disease can affect the eyes – here’s what we know so far
General Research
28 September 2020
Evaluation of LamPORE rapid tests for Covid-19 show high levels of diagnostic sensitivity
Coronavirus COVID-19 Research
25 September 2020
Scientists from the University of Oxford’s Nuffield Department of Medicine have today published their evaluation of LamPORE, a novel diagnostic platform for detecting SARS-CoV-2 RNA. It combines loop-mediated isothermal amplification with nanopore sequencing. This technology has the potential to analyse thousands of samples per day on a single instrument.
Oxford’s OpenABM-Covid19 mathematical model helps UK and other countries to control the coronavirus epidemic
Coronavirus COVID-19 Research
22 September 2020
Key discovery in Psoriatic Arthritis points way for developing targeted treatments
General Research
21 September 2020
A new study has revealed psoriatic arthritis may be activated by the same trigger in different patients. Researchers from the University of Oxford and the Wellcome Sanger Institute identified high levels of a specific receptor in immune cells from psoriatic arthritis patients, giving the strongest evidence yet of a single cause for the disease.
PRINCIPLE Trial to strengthen Black, Asian and minority ethnic community participation
Coronavirus COVID-19 General Research
18 September 2020
Professor Mahendra G Patel, University of Bradford, joins PRINCIPLE Trial as National Black, Asian and minority ethnic Community and Pharmacy Lead
Scientists discover what happens in our brains when we make educated guesses
General Research
17 September 2020
Researchers have identified how cells in our brains work together to join up memories of separate experiences, allowing us to make educated guesses in everyday life.
More than half of Year 12 students report poor mental wellbeing since lockdown
Coronavirus COVID-19 Research
16 September 2020
A school-based survey of students in Berkshire, Buckinghamshire, Gloucestershire, Oxfordshire and Wiltshire examined over 200 key factors in the lives and expectations of young people, aged 8-18 years, helping to shed light on mental health during lockdown.
New £4m study to advance our understanding of severe coronavirus infection
Coronavirus COVID-19 Research
16 September 2020
The University of Liverpool is leading a major new international project to improve our understanding of severe coronavirus infection in humans, together with collaborators from the University of Oxford, Public Health England, the University of Bristol; A*STAR in Singapore; and King Fahd Medical City in Saudi Arabia.
Study finds that high levels of a growth factor increases risk for several cancers
General Research
15 September 2020
A study of almost 400,000 British participants has identified a new link between raised levels of the growth factor IGF-1 and increased thyroid cancer risk and has confirmed associations with breast, prostate and colorectal cancer.
Children from low income backgrounds show elevated mental health difficulties throughout lockdown
Coronavirus COVID-19 General Research
14 September 2020
Emotional difficulties were consistently elevated among children and young people from low income households over a month of lockdown compared to those from higher income households.
RECOVERY COVID-19 phase 3 trial to evaluate Regeneron’s REGN-COV2 antibody cocktail
Coronavirus COVID-19 General Research
14 September 2020
One of the world’s largest efforts to find effective COVID-19 treatments will evaluate the impact of REGN-COV2 on mortality, hospital stays, and the need for ventilation.
Global consortium launches new study into long-term effects of COVID-19
Coronavirus COVID-19 General Research
14 September 2020
The International Severe Acute Respiratory and emerging Infection Consortium (ISARIC), based at Oxford University, in collaboration with Dr Janet Scott, of the MRC-University of Glasgow’s Centre for Virus Research, has launched a longitudinal observational study to measure prevalence and risk factors of long-term health and psychosocial consequences of COVID-19. The researchers are inviting hospitals and healthcare sites worldwide to join this new study.
The timing of COVID-19 transmission
Coronavirus COVID-19 General Research
11 September 2020
Understanding the timing of transmission dynamics of Covid-19 is crucial for optimising public health interventions and reducing the burden on communities.