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An internationally recognised centre of excellence for biomedical and clinical research and teaching
Research into ancient DNA sheds new light on cause of Multiple Sclerosis and other neurodegenerative diseases
General Research
11 January 2024
Research led by scientists at the Universities of Oxford, Cambridge, Copenhagen, Bristol and California (Berkeley) reveals the evolutionary origins of multiple sclerosis (MS). This new insight into the genetic architecture of this disease changes scientists’ view of its causes and has implications for its treatment, as well as paving the way for further investigations into other diseases.
Study shows that the way the brain learns is different from the way that artificial intelligence systems learn
General Research
8 January 2024
Researchers from the MRC Brain Network Dynamics Unit and Oxford University’s Department of Computer Science have set out a new principle to explain how the brain adjusts connections between neurons during learning. This new insight may guide further research on learning in brain networks and may inspire faster and more robust learning algorithms in artificial intelligence.
What is selective mutism? And is it a lifelong condition?
General Research
8 January 2024
Selective mutism is an anxiety disorder characterised by a consistent pattern of silence in specific social situations where speech is expected (for example, at school or work) while the person is able to speak comfortably in other situations.
Early-life diseases linked to lifelong childlessness
General Research
19 December 2023
A ground-breaking study, published in Nature Human Behaviour, reveals a significant association between 74 early-life diseases and the likelihood of remaining childless throughout one's life, with 33 of these diseases prevalent in both women and men.
Study shows diverse gut bacteria communities protect against harmful pathogens by nutrient blocking
General Research
15 December 2023
A new study led by the the Departments of Biology and Biochemistry at the University of Oxford, has demonstrated that diverse communities of resident bacteria can protect the human gut from disease-causing microorganisms. The researchers found that protective communities block the growth of harmful pathogens by consuming nutrients that the pathogen needs. The findings, published today in the journal Science, could help to develop new strategies to optimise gut health.
Researchers define new class of regulatory element in DNA
General Research
15 December 2023
Researchers at the MRC Weatherall Institute of Molecular Medicine's Laboratory of Gene Regulation, led by Professor Doug Higgs and Dr Mira Kassouf have published a study in the journal Cell, in which they reveal another piece of the puzzle of how the code in our DNA is read. In this study, the authors introduce the concept of “facilitators”, a newly identified type of non-coding DNA that can help to drive gene expression.
Ancient DNA reveals how a chicken virus evolved to become more deadly
General Research
15 December 2023
An international team of scientists led by geneticists and disease biologists from the University of Oxford and Ludwig-Maximilians-Universität München (LMU) have used ancient DNA to trace the evolution of Marek's Disease Virus (MDV). This global pathogen causes fatal infections in unvaccinated chickens and costs the poultry industry over $1 billion per year. The findings, published today in the journal Science, show how viruses evolve to become more virulent and could lead to the development of better ways to treat viral infections.
Blood collected through skin offers reliable testing method in children with type 1 diabetes
General Research
13 December 2023
Transdermal sampling – collecting blood through the skin – is a reliable alternative to taking blood samples from a vein with a needle in children with type 1 diabetes (T1D), new research has found.
Oxford scientist to lead international transdisciplinary consortium towards delivering NetZero Healthcare
General Research
13 December 2023
The European Union Horizon Europe (with joint funding from UK Research Innovation) has awarded NetZeroAICT Consortium major funding to develop a novel technology with great potentials to promote climate neutral and sustainable health care.
Oxford Vaccine Group, Department of Paediatrics, University of Oxford receives £7.8 million in research funding to fight pandemic and epidemic threats
General Research
13 December 2023
Oxford Vaccine Group (OVG), which led the rapid clinical development of the Oxford vaccine in COVID-19 in the pandemic, has been awarded a total of £7,788,783 by UK Aid for research into the prevention of five dangerous diseases with epidemic or pandemic potential. The awards will fund research into vaccines against: Chikungunya and mayaro virus, Marburg virus, Plague (Yersinia pestis), Q Fever (Coxiella burneti) and Sudan Ebolavirus.
Oxford University Hospitals launches new mRNA cancer vaccine trial for patients with head and neck cancers
General Research
11 December 2023
The first patient in Oxfordshire has been treated in an mRNA cancer vaccine trial at Oxford University Hospitals NHS Foundation trust (OUH). The trial, led locally by Dr Ketan Shah, consultant clinical oncologist at OUH, marks a significant milestone in the national cancer vaccine advance.
Antibiotic resistance genes are spread more widely between bacteria than previously thought
General Research
8 December 2023
A new study published in The Lancet Microbe has found that the transfer of antibiotic resistance genes between different bacteria is considerably more widespread than previously thought.
Race to cure type 1 diabetes gets a new boost
General Research
7 December 2023
Radcliffe Department of Medicine (RDM) group awarded £2.55 million for diabetes research.
Researchers develop a blood test to identify individuals at risk of developing Parkinson’s disease
General Research
5 December 2023
Research carried out at the University of Oxford has led to the development of a new blood-based test to identify the pathology that triggers Parkinson’s disease before the main symptoms occur. This could allow clinicians to screen for those individuals at high risk of developing the disease and facilitate the timely introduction of precision therapies that are currently at clinical trial stage.
Nuffield Department of Population Health’s Dr Tammy Tong awarded a UKRI Future Leaders Fellowship
General Research
4 December 2023
Armed to the hilt: Study solves mystery behind bacteria’s extensive weaponry
General Research
1 December 2023
A new study led by the University of Oxford has shed light on why certain species of bacteria carry astonishing arsenals of weapons. The new findings, published in the journal Nature Ecology & Evolution, could help us to engineer microbes that can destroy deadly pathogens, reducing our reliance on antibiotics.
Kennedy Trust gift to help drive forward research into inflammatory and musculoskeletal diseases at Oxford
General Research
30 November 2023
Two professorships in translational medicine have been endowed at the Kennedy Institute of Rheumatology thanks to a generous gift from the Kennedy Trust for Rheumatology Research.
Clinicians, practices, and patients all have a part to play in dealing with risks of remote consulting, new Oxford-led study reveals
General Research
29 November 2023
While most remote GP consultations are safe, the 'Remote by Default' study finds that GP consultations conducted remotely carry more risk for patients with some urgent conditions.
Nuffield Department of Primary Care Health Sciences set to deliver clinical trials expertise to China National Biotec Group in new collaboration
Clinical Trials General Research
28 November 2023
The training initiative builds the foundations to explore further collaborations encompassing joint research efforts, leadership programmes, and a shared commitment to advancing clinical trials.
Oxford-Harrington Rare Disease Centre named in first global initiative for children with rare diseases
General Research
27 November 2023
In the autumn statement on Wednesday 22 November, the government announced its support for the Rare Therapies Launch Pad, a new programme that will develop regulatory pathways for children with rare conditions to access individualised therapies.