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An internationally recognised centre of excellence for biomedical and clinical research and teaching
The RECOVERY Trial - two years on
Coronavirus COVID-19 General Research
23 March 2022
One trial. Over 47,000 participants. Nearly 200 hospital sites, across six countries. Ten results. Four effective COVID-19 treatments. And behind them all, an army of countless researchers, doctors, nurses, statisticians and supporting staff.
Largest genetic study of pleural infection reveals complex nature of common disease
General Research
21 March 2022
A new genetic study of the bacteria that cause pleurisy has shown most cases involve more than one type of bacterium, and revealed which bacterial combinations cause the most serious infections.
No link found between COVID-19 vaccines and neurological events
Coronavirus COVID-19 General Research
16 March 2022
Researchers from Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences (NDORMS) found no evidence that COVID-19 vaccines cause neurological disorders. But they did find an increased risk for unvaccinated people infected with SARS-CoV-2.
Oxford researchers awarded funding to study the immune response to malaria
Awards and Appointments General Research
15 March 2022
Professors Matthew Higgins and Michael Dustin from the University of Oxford, Prof Gavin Wright from the University of York, and Professors Shiroh Iwanaga and Hisashi Arase from Osaka University have secured a Wellcome Collaborative Award for their study “How do RIFINs and STEVORs modulate human immunity during malaria?”
Oxford leads global cross-collaboration Covid research
Coronavirus COVID-19 General Research
14 March 2022
A new collaboration between Oxford, Brazil and Pakistan has been funded by the Bill & Melinda Gates Foundation. The partnership will provide researchers with de-identified health data from two of the worlds global COVID-19 hotspots to increase understanding of COVID-19 in these communities and help accelerate the management of the disease.
New gene target identified to prevent tumour growth under acidity
General Research
11 March 2022
New research from Department of Physiology, Anatomy and Genetics (DPAG) has identified a new gene that allows cancer cells to survive in the typically acidic microenvironment of a malignant tumour. Researchers have discovered drugs that inhibit the gene in other medical conditions also selectively kill cancer cells at acidic pH, without damaging healthy tissue. This defines a novel strategy for targeting acidic tumour regions.
First UK pilot study of newborn screening for spinal muscular atrophy (SMA) launched in Oxford
General Research
11 March 2022
In the UK, every 5 days a baby is born with SMA. Treatments are available now. If these treatments are delivered at birth, these newborns have the best chance of living long and healthy lives. If treated later, when they are identified because of the symptoms, they may survive, but with a severe disability. So, for every 5 days that a newborn screening is delayed, a baby in the UK loses the chance of a brighter future.
Exscientia and University of Oxford launch “Xcellomics” program to expedite early-stage academic research and translate novel biology into future drug discovery
General Innovation Research
10 March 2022
Exscientia and the University of Oxford's Target Discovery Institute (TDI) today announced the formation of Xcellomics – a program designed to source cellular functional assays from the global academic community to develop novel screens and identify targets and therapeutic candidates for unmet medical needs.
Professor Lynne Cox helps lead UK project to transform older age health
General Research
9 March 2022
Professor Lynne Cox of the Department of Biochemistry will co-lead a new national research network focused on transforming the health of older people and boosting the economy.
Oral paratyphoid vaccine to begin human trials
General Research
9 March 2022
The University of Oxford in collaboration with the University of Maryland School of Medicine (UMSoM) has begun recruiting for a Phase I/II trial of a new paratyphoid vaccine in human volunteers in Oxford.
Brain regions related to smell show decline following mild COVID-19
Coronavirus COVID-19 General Research
8 March 2022
Researchers from the University of Oxford have used data from UK Biobank participants to look at changes to the brain on average 4.5 months after mild SARS-CoV-2 infection.
NIHR awards Oxford Health Clinical Research Facility £4 million over next five years
Awards and Appointments General Research
7 March 2022
The Oxford Health Clinical Research Facility (OH CRF) is one of 28 facilities across England to benefit from nearly £161 million that has been awarded by the National Institute for Health Research (NIHR) to expand early phase clinical research delivery in NHS hospitals.
RECOVERY trial shows Baricitinib reduces deaths in patients hospitalised with COVID-19
Coronavirus COVID-19 General Research
7 March 2022
The Randomised Evaluation of COVID-19 Therapy (RECOVERY) trial has demonstrated that baricitinib, an anti-inflammatory treatment normally used to treat rheumatoid arthritis, reduces the risk of death when given to hospitalised patients with severe COVID-19.
Rabies vaccine candidate begins human trials in Tanzania
General Research
7 March 2022
The University of Oxford and the Ifakara Health Institute today announced the vaccination of the first participants in a Phase Ib/II trial testing a novel rabies vaccine in human volunteers in Tanzania.
COVID-19 Multi-omic Blood Atlas (COMBAT) published
General Research
3 March 2022
The COVID-19 Multi-omic Blood Atlas (COMBAT) defines hallmarks of disease severity and specificity
Professor Collins awarded Sir Jules Thorn Translational Biomedical Research Award 2021
Awards and Appointments General Innovation Research
2 March 2022
Professor Sally Collins has been awarded the prestigious and highly competitive Sir Jules Thorn Translational Biomedical Research Award 2021 for further translational development of the OxNNet Toolkit.
Funding boost for early-stage clinical research
General Research
1 March 2022
Oxford is one of 28 sites that will benefit from over £160 million awarded over five years to expand early phase clinical research for the benefit of NHS patients.
New study shows significant impacts of severe COVID-19 infection on pregnancy outcomes
Coronavirus COVID-19 General Research
1 March 2022
A new analysis from Oxford Population Health has found that pregnant women that are 30 years old or more, overweight, of mixed ethnicity or have gestational diabetes have a greater risk of contracting severe COVID-19, which poses significant risks for both mother and baby.
University of Oxford researchers create largest ever human family tree
General Research
28 February 2022
Researchers from the University of Oxford’s Big Data Institute have taken a major step towards mapping the entirety of genetic relationships among humans: a single genealogy that traces the ancestry of all of us.
Researchers find genetic ‘fingerprints’ of ancient migrations in modern-day United Arab Emirates
General Research
23 February 2022
A team of geneticists and archaeologists have analysed the fine-scale genetic structure and ancestry of nearly 1200 people from the United Arab Emirates (UAE), and found genetic traces of population mixing spanning thousands of years.