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An internationally recognised centre of excellence for biomedical and clinical research and teaching
Oxford spinout Brainomix is revolutionising stroke care through AI
General Innovation Research
16 February 2024
This year, around 100,000 people in the UK will have a stroke. AI algorithms developed by a University of Oxford spinout company are ensuring that more stroke patients will receive better care and outcomes.
Online tool that empowers parents to treat child anxiety could expand access to child mental health services
General Research
9 February 2024
New research from the University of Oxford has revealed that an online program that empowers parents to apply Cognitive Behavioural Therapy (CBT) principles in their child’s day to day lives is just as effective as traditional talking therapies for child anxiety problems, while substantially reducing the amount of therapist time required and making support more accessible for many families. The approach provides parents online tools and some therapist guidance to help children overcome problems with anxiety.
Medical Sciences Interdivisional Research Ethics Committee (MS IDREC) seek external lay member
General Research
5 February 2024
New research improves accuracy of molecular quantification in high throughput sequencing
General Research
5 February 2024
A team at Nuffield Department of Orthopaedic Rheumatology and Musculoskeletal Sciences (NDORMS) has developed a new approach to significantly improve the accuracy of Ribonucleic acid (RNA) sequencing. They pinpoint the primary source of inaccurate quantification in both short and long-read RNA sequencing, and have introduced the concept of “majority vote” error correction leading to a substantial improvement in RNA molecular counting.
World Cancer Day 2024: Highlighting Cancer Research at the Medical Research Council Weatherall Institute of Molecular Medicine (MRC WIMM)
General Research
4 February 2024
This World Cancer Day, we heard from four Group Leaders at the MRC Weatherall Institute of Molecular Medicine about their work and how their groups are helping in the fight against cancer.
New phase 3 trial data confirm the uniquely high efficacy and good safety profile of the R21/Matrix-M malaria vaccine in African children
Clinical Trials General Research
1 February 2024
Investigators immunised over 4800 young children in a trial in Burkina Faso, Kenya, Mali and Tanzania and found on average 78% efficacy in the 5–17-month age group over the first year To date 25 million doses manufactured and ready for roll-out by The Serum Institute of India (SII) in the next three to four months
New data shows prevalence of Premenstrual Dysphoric Disorder
General Research
30 January 2024
Around 1.6% of women and girls have symptomatic Premenstrual Dysphoric Disorder (PMDD), according to a new review of global studies published in the Journal of Affective Disorders.
New guidance published to aid researchers evaluating surgical robots
General Research
26 January 2024
Surgical robotics are amongst the most complex devices entering healthcare, but how should we evaluate them? Published in Nature Medicine, the Idea, Development, Exploration, Assessment and Long-term monitoring (IDEAL) Robotics Colloquium outlines the latest guidance to aid researchers evaluating surgical robots.
Researchers develop easy-to-deploy federated learning system that safeguards patient data
General Research
25 January 2024
Researchers in Oxford have developed a new, easy-to-use technique for hospitals to contribute to the development of artificial intelligence (AI) models, without patient data leaving the hospital’s premises.
Study assesses long-term risk of invasive breast cancer after pre-invasive disease
General Research
25 January 2024
Women who are diagnosed with ductal carcinoma in situ (DCIS) outside the National Health Service breast screening programme are around four times as likely to develop invasive breast cancer and to die from breast cancer than women in the general population, finds a University of Oxford study published by the British Medical Journal (BMJ)
New reporting guideline will provide transparency in consensus research
General Research
24 January 2024
Published in The Public Library of Science (PLOS), the new guideline will help the scientific community to write complete and transparent research reports involving consensus methods.
Using Innovation Enhancing Techniques (IETs) as a framework for creative solutions
General Research
22 January 2024
Medical student, Anuraag Vazirani, and fellow colleagues from St Cross College, recently published a paper in the journal Scientific Reports, in which they introduce Innovation Enhancing Techniques (IETs) to address challenges in healthcare and biomedicine, offering a versatile framework for creative solutions. Their study aims to give entrepreneurs, innovators, and researchers a toolkit to create innovative solutions to problems they are trying to solve. By adapting a technique called 'BrainSwarming', which enables a problem-solver to overcome psychological obstacles to thinking up new solutions to a problem, they can effectively generate innovative solutions - an alternative to traditional 'brainstorming'.
Research uncovers mechanism behind stubborn memories
General Research
22 January 2024
Researchers from the Medical Research Council Brain Network Dynamics Unit at the University of Oxford and the Nuffield Department of Clinical Neurosciences have identified a novel mechanism by which the brain produces powerful lasting memories that drive ill-advised actions.
Innovative Imaging solution offers potential breakthrough in endometriosis detection
General Innovation Research
19 January 2024
The DETECT study, led by Nuffield Department of Women's and Reproductive Health Professors Christian Becker and Krina Zondervan explores the potential of visualizing endometriosis, including hard-to-detect superficial peritoneal disease, using Serac's innovative imaging agent.
Study highlights importance of ‘junk’ DNA in unlocking diagnosis
General Research
18 January 2024
A recent study led by the Centre for Human Genetics at the Nuffield Department of Medicine has revealed that areas of the human genome that are routinely overlooked in clinical tests may be the cause of some rare diseases.
Lymph node research pioneers’ new approach to vaccine design for the most vulnerable
General Research
17 January 2024
The Oxford Experimental Medicine Clinical Research Facility (EMCRF) at Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences (NDORMS) has received its first volunteers as part of the LEGACY03 trial to improve vaccine design for different age groups.
Novel inhaled TB vaccine
General Research
16 January 2024
The Jenner Institute is conducting a new study, using BCG, the current licensed vaccine against tuberculosis. In this study, they will give BCG a second time to people who have already had BCG once before, and will compare whether giving it by inhalation is better at protecting people against tuberculosis than giving it into the skin
Research into ancient DNA sheds new light on cause of Multiple Sclerosis and other neurodegenerative diseases
General Research
15 January 2024
Research led by scientists at the Universities of Oxford, Cambridge, Copenhagen, Bristol and California (Berkeley) reveals the evolutionary origins of multiple sclerosis (MS). This new insight into the genetic architecture of this disease changes scientists’ view of its causes and has implications for its treatment, as well as paving the way for further investigations into other diseases.
First-in-human vaccine trial for deadly Nipah virus launched
General Research
12 January 2024
First clinical trial participants received doses of the ChAdOx1 NipahB vaccine over the last week at University of Oxford. UK trial is first step to developing a vaccine against Nipah virus – a devastating disease mostly found in South-East Asia – that can be fatal in up to 75% of cases. The milestone clinical trial comes as the global health community marks the 25th anniversary of the first Nipah virus outbreaks. There are still no approved vaccines or treatments for the disease.
COVID-19 vaccines found effective in reducing long COVID symptoms
General Research
12 January 2024
A recent study has revealed the effectiveness of COVID-19 vaccines in preventing long COVID