Previously funded projects
- Development of UGGT1 inhibitors as broad-spectrum antivirals, Nicole Zitzmann (Department of Biochemistry)
- Development of an adeno-associated viral vectored immunoprophylactic strategy against blood-stage Plasmodium vivax Malaria, Martino Bardelli (Jenner Institute, Nuffield Department of Medicine)
- Developing small molecule inhibitors for a rare childhood seizure disorder, Wyatt Yue (Nuffield Department of Medicine, Structural Genomics Consortium)
- Harnessing the properties of a small compound to improve the efficiency of reprogramming dendritic cells to pluripotency, Paul Fairchild (Sir William Dunn School of Pathology)
- Deep Brain Stimulation for Multiple System Atrophy, Alex Green (Nuffield Department of Surgical Sciences)
- Structure-guided design of FAM83B inhibitors for triple negative breast cancer, Alex Bullock (Nuffield Department of Medicine)
- MICA: Reprogramming tumor immunity by targeting tenascin-C, Kim Midwood (Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences)
- T-cell receptor-like antibodies targeting p53, Alison Banham (Radcliffe Department of Medicine)
- Polymer-DNA nanoparticles for Therapeutic Intracellular Delivery, Andrew Turberfield (Department of Physiology, Anatomy and Genetics)
- Orthotopic colorectal cancer patient-derived xenograft models to test therapeutic manipulation ofGREM1, Simon Leedham (Nuffield Department of Medicine)
- Structure-Guided Design of Sonic Hedgehog Morphogen Inhibitors, Christian Siebold (Nuffield Department of Medicine)
- Proof-of-concept controlled human infection with Plasmodium vivax malaria to accelerate Phase II clinical trials of vaccine candidates, Angela Minassian (Nuffield Department of Medicine)
- How does BCG vaccination facilitate protection against malaria? Anita Milicic (Nuffield Department of Medicine)
- CMV-vectored vaccines: second generation vectors with improved safety profile, Sarah Sebastian (Nuffield Department of Medicine)
- Development of a novel bivalent vaccine to prevent both Salmonella Typhi and Paratyphi infections, Christine Rollier (Department of Paediatrics)
- Ultrasonic electrospray of intact complexes from vesicles and exosomes, Carol Robinson (Department of Chemistry - Mathematical, Physical & Life Sciences Division)
- Non-invasive estimation of pulmonary blood flow in primary pulmonary hypertension, Peter Robbins (Department of Physiology, Anatomy and Genetics)
- New approaches to microsphere formulation for single dose prime-boost vaccine delivery, Anita Milicic (Nuffield Department of Medicine)
- Utilising immune-dominant epitopes of limited variability to create a novel influenza vaccine, Sunetra Gupta; Department of Zoology - Mathematical, Physical & Life Sciences Division)
- Development of UGGT1 inhibitors as broad-spectrum antivirals, Nicole Zitzmann (Department of Biochemistry)
- The development of pan-genotypic Hepatitis C virus vaccine generating T and B cell immunity, Eleanor Barnes (Radcliffe Department of Medicine)
- A universal H1N1 influenza vaccine using an epitope of limited variability: Sunetra Gupta; Department of Zoology - Mathematical, Physical & Life Sciences Division)
- A flexible and scalable platform for creating novel medicinal macrocycles, James Naismith (Nuffield Department of Medicine)
- Pre-clinical development of therapeutic cross-reactive monoclonal antibodies to Ebola viruses, Pramila Rijal (Radcliffe Department of Medicine)
- Structure based beta-Lactamase resistant transpeptidase inhibitors to address antibiotic resistance: Christopher Schofield (Department of Chemistry - Mathematical, Physical & Life Sciences Division)
- Polymeric-DNA nanoparticles: modular delivery systems for nucleic acid-based therapies: Andrew J Turberfield (Department of Physics - Mathematical, Physical & Life Sciences Division)
- Measuring lung inhomogeneity in paediatric cystic fibrosis, Grant A.D. Ritchie (Department of Chemistry - Mathematical, Physical & Life Sciences Division)
- Universal Big DNA assembly: transition to a translatable high throughput process, Christopher O'Callaghan (Nuffield Department of Medicine)
- Using DNA-based diagnostics to prevent death of children with blood disorders in sub-Saharan Africa, Anna Schuh (Department of Oncology)
- Using genome variation to sort extremely rare cell populations for clinical application, John Frater (Nuffield Department of Medicine)
- Antibody-mediated oligonucleotide delivery to brain for neurodegenerative disease, Suzan Hammond (Department of Paediatrics)
- CAT&MAUS: simultaneous imaging and analysis of joint motion for clinical assessment: Stephen Mellon (Nuffield Department of Orthopaedics, Rheumatology & Musculoskeletal Sciences)
- GAPDH and extracellular vesicles: biological nanoparticles for therapy of neurodegenerative diseases: Ghulam Dar (Department of Paediatrics)
- Proteomic biomarkers in IBD, Alexander Adams(Nuffield Department of Medicine)