Find a Supervisor by name

Browse A-Z by surname    [Show all]
Oreste Acuto

The biochemical basis of signal initiation and propogation, its fine tuning and stabilization that imparts during phenotypic changes.

Dragana Ahel

SNF2 ATPases in genome stability and cancer

Ivan Ahel

DNA damage response mechanisms

Ahmed Ahmed

Ovarian Cancer

Anne Aimola Davies

Neuropsychology of visual and somatosensory attention

Colin Akerman

RESEARCH AREAS: Neurotransmission in the developing central nervous system, Activity-dependent plasticity of developing axons and dendrites, Molecular aspects of synapse formation and related neurodevelopmental disorders, Balancing neural excitation and inhibition in development and in epilepsy.

Bungo Akiyoshi

Evolutionary cell biology of chromosome segregation

Brian J Angus

Malaria, HIV and Melioidosis

Olaf Ansorge

Comparative studies of human and murine neuropathology of neurodegeneration

Daniel Anthony

How mediators of the inflammatory response contribute to the outcome of spinal or brain injuries. How events in others organs, such as the liver, contribute to the outcome of brain injury or disease. In particular (with the Neuroimaging group), we are studying the mechanisms that give rise to the reactivation of a Multiple sclerosis-like lesions by a systemic inflammatory response. How brain injury contributes to the outcome of disease elsewhere in the body with a focus on how hepatic NFkB activity contributes to the acute phase response after CNS injury (with Dr Mann, Southampton). How inflammation affects brain serotonin function and the relevance to depression (with Dr Sharp and the Neuroimaging group).

Charalambos Antoniades

Crosstalk between adipose tissue and vascular/myocardial redox state in humans: Pharmacological interventions

Nigel Arden

Epidemiology & pathophysiology of osteoarthritis & osteoporosis; clinical trials in common musculoskeletal conditions; Role of vitamin D in musculoskeletal health

Radu Aricescu

Structural biology of synaptic signalling

Judy Armitage

Flagellar rotation and intracellular signalling pathways controlling bacterial chemotaxis

Tal Arnon

Regulation of humoral immune responses by tissue resident macrophages

Frances Ashcroft

Ion channels, diabetes and obesity

Houman Ashrafian

Cell and Molecular Biology

Nicholas A Athanasou

All aspects of the physiology and pathology of bone and joint tissues, particularly osteoclast pathobiology

Jon Austyn

Immunobiology of dendritic cells

Colin N Baigent

Clinical trials, Meta-analysis, Epidemiology and Cardiovascular disease

Alison Banham

Therapeutic antibodies for cancer therapy. Transcriptional deregulation in lymphomagenesis.

David Bannerman

Behavioural Neuroscience

Ellie Barnes

Human Chronic Viruses

Francis Barr

Spatial and temporal control of mitosis and cytokinesisand control of membrane trafficking by Rab GTPases

Hagan Bayley

We are a chemical biology group which focuses on protein chemistry, molecular genetics and biophysics. Much of our work is centered on membrane proteins, in particular channels and pores.

David Beard

Identifying best treatment for knee arthritis sufferers across a broad range of severity and degeneration using kinematics, epidemiology, rehabilitation, outcome assessment, and clinical trials of various interventions for both early and late stage disease

Christian Becker

Endometriosis and ovarian cancer

Esther Becker

Understanding Cerebellar Development and Disease

David Beeson

Molecular Neurosciences

Timothy Behrens

Neuronal mechanisms of decision-making and measuring brain connections in the living human

Valerie Beral

Cancer Epidemiology and Women's Health

James Berkley

Global childhood infection & immunity

Ben Berks

Bacterial protein transport and bacterial energy metabolism

Angelyn Bethel

Health Evaluative Methodologies

Shoumo Bhattacharya

Cardiac development, congenital heart disease and mycardial homeostasis

Phil Biggin

Computational Approaches to Receptor Dynamics and Ligand-Binding

Liz Bikoff

Epigenetic regulators of embryonic development

Dorothy Bishop

Genetics, neurobiology and psychology of children's communication impairments

Sonia Bishop

Identifying neuro-cognitive mechanisms of human anxiety using task-related (associative learning, attentional function, decision making) and task-free (resting state, spectroscopy) MRI methods.

Walter Bodmer

Cancer & Immunogenetics Laboratory

Gareth Bond

Oxford Ludwig Institute

Jacqueline Boultwood

Molecular pathogenesis of the myelodysplastic syndromes (MDS), including the 5q- syndrome

Chas Bountra

Structure, function and drug target discovery

Paul Bowness

What is the role of HLA-B27 in the pathogenesis of spondyloarthritis?

Sven Braeutigam

Magnetoencephalography (MEG) and cognitive neuroscience

Holly Bridge

Investigating the normal an abnormal human visual system using magnetic resonance imaging

Neil Brockdorff

Developmental Epigenetics

Peter Brown

Understanding systems level dysfunction in Parkinson's Disease in order to improve therapy

Alastair M Buchan

Acute stroke and Neuroprotection

Veronica Buckle

Cell and Molecular Biology

Peter Bull

Immunity to and pathogenesis of Malaria

Daniel Bulte

Development of clinically viable, calibrated FMRI

Amanda Burls

Director of Postgraduate Programmes in Evidence-Based Health Care

Phil Burnet

The molecular neurobiology of D-amino acids and their relevance to schizophrenia

Tom Burns

Socal Psychiatry

Martin Burton

Genetics and Therapy of Otitis Media

Andrew Bushell

Transplantation Research Immunology Group

Chris Butler

Human Memory and its impairment in neurological disease

Simon Butt

Interneuron development and function

James Byrne

Neurovascular disease

Zameel Cader

The role of aminoacyl-tRNA synthetases in neurodegeneration

Liz Carpenter

Protein Science and Structural Biology

Andrew J Carr

Surgical treatment of shoulder pain (Randomised Clinical Trials and Patient Reported outcome Measure development); Implant development (Shoulder replacement and Tendon tissue engineering scaffolds).

Carolyn Carr

Stem cell therapy for heart failure

Barbara Casadei

Nitric oxide/redox signalling in health and disease (e.g., myocardial ischaemia, diabetes, heart failure and atrial fibrillation)

Climent Casals-Pascual

A systems approach to malaria

Vincenzo Cerundolo

Vaccination, cancer immunology and NKT cell function

Steven Chance

Neuroanatomy & Cognition in Autism and Alzheimer's disease.

Keith Channon

Nitric oxide and redox signalling in cardiovascular disease

Stephen Chapman

Lung infection and genomics

Zhengming Chen

Kadoorie Biobank Study

Tim Child

Oocyte in-vitro maturation (IVM), IVF, PCOS, reproductive failure, endometriosis, laparoscopy

Robin Choudhury

Development and application of magnetic resonance imaging to characterize atherosclerosis and vascular disease. Interventions to retard progression and induce regression of atherosclerosis

John Christianson

ER-associated degradation and regulation of the secretory pathway

Grant Churchill

Determinations of cyclic ADP-ribose and NAADP levels. Endogenous synthesis and metabolism of NAADP. Signal transduction pathway underlying NAADP production. Spatial and temporal control of calcium increases by NAADP. Physiological roles of NAADP and lysosome-related calcium-storing organelles. Development of caged and cellpermeant messengers.

Stuart Clare

Ultra-high field MRI physics

David M Clark

Social Anxiety Disorder and Post-traumatic Stress Disorder, Cognitive Processess and Treatments

Robert Clarke

Cardiovascular Risk and Epidemiology

Roi Cohen Kadosh

Neurocognitive mechanisms of mathematics, synaesthesia, and cognitive control; cognitive enhancement.

Martin Cohn

Maintenance of genomic stability and DNA repair in humans

Rory E Collins

Clinical Epidemiology and the UK Biobank

Christodoulides Constantinos

Cell and Molecular Biology

Cyrus Cooper

Developmental influences contributing to the risk of osteoporosis and hip fracture in late adulthood, Incidence rates of vertebral fractures, Role of Vitamin D insufficiency in bone mineral accrual in childhood

Zafra Cooper

Eating disorders

Richard Copley

Bioinformatics, Gene Function

Richard, J Cornall

Autoimmunity and Immune Regulation Group

Kevin Coward

Sperm structure and function, egg activation, male factor infertility

Phil Cowen

Pathophysiology, treatment and prevention of mood disorders- neurobiological aspects

Lynne Cox

Replicative senescence: towards an understanding of cellular ageing

Roger Cox

Genetics of Type 2 Diabetes

Stephanie Cragg

Understanding dopamine neurotransmission in the basal ganglia and reward-related centres and its dysfunction in neurodegenerative disorders and drug addiction.

Catherine Crane

Psychological models and treatment of recurrent depression and suicidality; mindfulness-based approaches to prevention of depression and enhancing well-being

Matthew Craner

Fast-track neuroprotective studies in MS

David Cranston

Renal cancer

Derrick Crook

Infectious Disease

Francesca Crowe

Clinical Epidemiology

Matthew Daniels

Using light and magic to understand inherited heart disease

Sarah C Darby

Cancer Epidemiology

Ben Davies

Transgenic Technology Research Group

Kay E Davies

Molecular analysis of neurological disorders

Ilan Davis

mRNA Localisation in Drosophila

Simon J Davis

T-cell Biology Group

Nick PJ Day

Mahidol-Oxford Tropical Medicine Research Unit

Marella de Bruijn

Hematopoietic stem cell generation during embryonic development

Sarah De Val

Angiogenesis Group

Robert Deacon

Hippocampal and cortical function: cognition, emotionality, species-typical behaviours, motor behaviours. Prion and Alzheimer's Disease, animal models. Mice, rats, animal welfare.

Jonathan Dean

Cell Signalling and Post-Transcriptional Regulation in Inflammation

Grigory Dianov

Our long-term goal is to study the proteins and mechanisms involved in the coordination and regulation of base excision repair, to unravel their role in the repair of radiation induced DNA damage and to examine the relationship to human diseases, such as cancer.

Tao Dong

Anti-viral T cell response

Peter Donnelly

Statistical Genetics

Kim Dora

Vascular endothelial cell function in health and disease.

Lucy Dorrell

Immune modulation in HIV infection

Hal Drakesmith

Iron and infection

Simon J Draper

Blood-Stage Malaria Vaccine Group

James Dunford

Characterisation of mevalonate pathway enzymes, putative pyrophosphate transport protein ANKH & molecular pharmacology

Omer Dushek

Systems Biology of Lymphocyte Signaling

Mike Dustin

The immunological synapse and integrating this into the 3D tissue context

Raymond Dwek

Glycobiology, proteomics, antivirals

Klaus Ebmeier

Neurobiology of Ageing and psychological disorders in old age

Claire Edwards

Research interests are focused upon the pathogenesis of cancer-induced bone disease, including the contributions of the host bone marrow microenvironment and the role of obesity, adipocytes and adipokines

James Edwards

Ageing process and musculoskeletal degeneration

Christian Eggeling

Nano-Immunology

Elma Tchilian

Immunology

Nigel Emptage

Basic synaptic transmission. Synaptic plasticity. Intracellular calcium signalling in the specializations of central synapses

Mike English

Improving delivery of evidence based care for severely ill children

Fumiko Esashi

Regulation of DNA repair by cell cycle regulators

Robert M Esnouf

Bioinformatics of protein structures

Jeremy Fairbank

Effectiveness of different treatments for degenerative diseases of the spine; understanding the processes underlying back pain and scoliosis

Christopher Fairburn

Eating disorders

Paul Fairchild

Addressing the immunological barriers to stem cell therapies.

Andrew Farmer

Much of the research that Professor Farmer has recently led or collaborated on aims to improve the effectiveness of tests and treatments for people with diabetes, for example the use of telehealth to support self-management in diabetes, although recent trials also include evaluation of telehealth support for people with COPD, and use of text messaging to support treatment adherence in hypertension.

Andrew Farmery

Mathematical modelling of gas exchange in the diseased lung. Development of novel technologies in clinical monitoring.

Martin Farrall

The molecular basis and population genetics of multifactorial cardiovascular disease and associated quantitiative (intermediate) phenotypes

Jeremy Farrar

Oxford University Clinical Research Unit, Viet Nam

Seena Fazel

Risk factors for violent crime in severe mental illness

Stephan Feller

The Biological Systems Architecture Group

Stuart Ferguson

Structure function and biogenesis of bacterial respiratory proteins

Panagis Filippakopoulos

Protein Science and Structural Biology

Ray Fitzpatrick

Professor of Public Health and Primary Care and Head of the Department of Public Health, University of Oxford.

Jonathan Flint

Psychiatric Genetics

Ervin Fodor

Influenza virus replication at the molecular level.

John Frater

HIV Infection

Daniel Freeman

The cognitive understanding and treatment of delusions and hallucinations

Matthew Freeman

Cell biology of signalling in development and disease

Peter Friend

Isolated organ perfusion and preservation. Clinical trials of novel Immunosuppression.

Lars Fugger

Multiple sclerosis

Tudor Fulga

Non-coding RNAs in development and disease

Andre Furger

Control of gene expression in eukaryotes

Antony Galione

Regulation of intracellular channels Calcium-mobilising second messengers, Cyclic ADP-ribose and NAADP as second messengers, Organization of intracellular Ca2+ signals, Molecular characterization of novel calcium release channels, Molecular signaling at fertilization, Stimulus-secretion coupling in exocrine and endocrine pancreas Excitation-contraction coupling in striated and smooth muscle Role of acidic calcium stores in calcium signaling

Chris Garland

Pharmacology of vascular smooth muscle and endothelial cells.

Elspeth Garman

Radiation damage in X-ray crystallography and elemental analysis of proteins

Kevin Gatter

Angiogenesis, non angiogenesis, molecular analysis, gene expression profile, lung cancer

John Geddes

Evidence-based mental health

Richard Gibbons

Chromatin remodelling factors in human disease

Robert JC Gilbert

Ribosomes, membrane and pore-forming proteins, viruses

Sarah C Gilbert

Vaccine Development

Opher Gileadi

Biotechnology and Genome Integrity

Matthew Giles

Transient ischaemic attack and minor stroke

Deborah Gill

Gene Therapy for Lung diseases

Richie H Gill

Development, diagnosis and treatment of joint disease using image processing, mechanical testing, mathematical modelling, computer simulation, finite element analysis, motion analysis, computer science and statistical modelling combined with clinical and biological studies

Geraldine Gillespie

The molecular and epigenetic biology of NK cells

Maike Glitsch

Transduction cascades involved in cerebellar signalling in health and disease, transduction pathways (G-protein coupled receptors and ion channels)

Anna L Gloyn

The genetics and functional biology of Type-2 diabetes & related traits

Eva Gluenz

Cell biology of Leishmania; role of the flagellum in host-parasite interactions

Sion Glyn-Jones

Mechanics of hip osteoarthritis, mechanisms of bearing surface wear and prosthesis failure & clinical and radiostereometric studies to evaluate new designs of hip arthroplasty

Deborah Goberdhan

Outreach Find out more about the Goberdhan Group outreach activities here .

Colin, R Goding

Cancer, development and stem cell biology

Guy Goodwin

The neurobiology and treatment of mood disorders

Stephen Gough

Genetics and Genomics

Philip Goulder

Paediatric HIV T cell immunology

Ron Gray

Maternal and child health inequalities I carry out evidence synthesis through systematic reviews and secondary analysis of well established cohort studies such as the Millenium Cohort Study, the Avon Longitudinal Study of Parents and Children and analysis of routinely collected maternity statistics. My primary interests are in socially generated health inequalities and the teratogenic effects of alcohol on the fetus.

David Greaves

Inflammation Biology.

Alexander Green

Investigation of autonomic function and pain physiology in human patients undergoing deep brain stimulation

Jonathan M Grimes

dsRNA viruses

Natalia Gromak

Regulation of RNA metabolism in health and disease

Ulrike Gruneberg

Mechanisms regulating mitotic progression

Kay Grunewald

Structural cell biology of virus infection

Keith Gull

Aspects of the pathogenicity of African trypanosomes and inherited ciliary diseases of humans.

Monica Gullerova

Transcriptional gene silencing and its implication in human pathology

Alison Halliday

Large Clinical Trials investigating carotid artery interventions to prevent stroke Carotid Surgery Audit

Ester Hammond

The focus of my lab is the biological consequences of hypoxia initiating a DNA damage response in the absence of DNA damage.

Ashok Handa

Vascular Surgery and patient safety

Penny Handford

cbEGF containing proteins in health and disease

Linda Hands

Vascular surgery and telemedicine

Tomas Hanke

HIV-1 Vaccine Development Group

Catherine Harmer

Psychopharmacology of emotional disorders and treatments

Anthony Harnden

My clinical and research interests are in primary care paediatrics, specifically common childhood infection, vaccine preventable infection, the early diagnosis of serious disease and clinical trials in children.

Paul Harrison

Genetic and translational neurobiology of schizophrenia

Bass Hassan

Molecular and functional aspects of tumour growth, and how the molecules that control growth can be targeted for application to human cancer therapy.

Keith Hawton

Psychological and psychiatric aspects of medical illness and practice

Lisa Heather

Metabolism and function in the Diabetic and Infarcted Heart

Carl Heneghan

My research projects involve investigating the evidence base for publication bias and drug and device regulation. I also work on a number of projects with the BMJ related to the regulatory and evidence requirements for devices.

Miles Hewstone

Social Psychology

Matt Higgins

Structural studies of the malaria parasite

Doug Higgs

The regulation of gene expression during erythropoiesis

Adrian VS Hill

Jenner Institute / Infectious Diseases / Malaria Vaccine Trials

Ling-Pei Ho

The immunology of respiratory infections

Richard Hobbs

My research interests focus on cardiovascular epidemiology and clinical trials, especially relating to vascular and stroke risk, and heart failure. See my full biography at http://www.phc.ox.ac.uk/team/researchers/richard-hobbs

Jonathan Hodgkin

Genetics of nematode immunity and development

Leanne Hodson

Integrative Physiology (Systems Biology)

Georg Hollander

The Immunobiology of the Thymus and the T cell System

Rury R Holman

Diabetes Trials Unit (DTU)

Chris Holmes

Genetic Epidemiology

Emily Holmes

Experimental Psychology and Cognitive Therapy: Understanding mental imagery from PTSD flashbacks to Bipolar Disorder

Tim Holt

My research addresses the practical challenges of delivering evidence based primary health care in the modern NHS environment. I am particularly interested in the potential of routinely collected data to influence practice at the point of care, through innovative tools including software interventions.

Peter Horby

Oxford University Clinical Research Unit, Viet Nam

Mark Howarth

Bionanotechnology and its application to Cancer

Juha Huiskonen

Protein Science and Structural Biology

Philippa Hulley

Exploring survival and differentiation control pathways in skeletal cells. Research is directed towards understanding disease pathology and devising effective regenerative strategies

Tim Humphrey

Understanding how genome stability is maintained in response to DNA double-strand breaks.

Glynn Humphreys

The neuropsychology of vision and action - lesion-symptom mapping, fMRI and experimental studies. The effects of learning on binding (fMRI, TMS, neuropsychology). Social cognitive neuroscience (self-related prioritisation - TMS, fMRI, neuropsychology).

Masud Husain

Motivation and decision-making in brain disorders

Stephen Hyde

Gene Therapy for Lung diseases

Yoshifumi Itoh

The mechanism of cell invasion process in tissue degenerative diseases

David G Jackson

Lymphatics and cell trafficking

William James

HIV-Macrophage interactions and stem cell technology

Kassim Javaid

Epidemiology & pathophysiology of osteoarthritis & osteoporosis; clinical trials in common musculoskeletal conditions; Role of vitamin D in musculoskeletal health

Saad Jbabdi

Development of mathematical and computational tools for the analysis of brain imaging data

Mark Jenkinson

Development of mathematical and computational tools for the analysis of brain imaging data

Peter Jezzard

Development of magnetic resonance imaging (MRI) methodology and applications to biomedicine.

Heidi Johansen-Berg

Neuroimaging and brain stimulation to study learning and recovery of function

E. Yvonne Jones

Receptor Structure Research Group

Achillefs Kapanidis

Single molecule biophysics

Fredrik Karpe

Oxford Laboratory for Integrative Physiology (Oxlip)

Dominic Kelly

Paediatric vaccine immunology with particular interest in B-cell responses. Epidemiology of invasive bacterial disease and pneumonia in childhood.

James Kennedy

Geratology and Stroke Medicine

Stephen Kennedy

Women's health

David Kerr

Genetics and Genomics

Benedikt M Kessler

Ubiquitin Proteolysis Group

Tim Key

Cancer Epidemiology Unit

Anne Kiltie

The focus of my lab is the investigation of DNA damage signalling and DNA repair as they relate to the aetiology of bladder cancer and its response to radiotherapy and combined modality treatments.

Colin Kleanthous

Protein-protein interactions in bacterial cell signalling and protein import

Paul Klenerman

Antiviral immunity

Rob Klose

Epigenetic regulation of chromatin function

Stephan Knapp

Phosphorylation Dependent Signalling Biology Group

Julian C Knight

Functional genomics of inflammation and immunity

Samantha JL Knight

Gene Expression, indels and genome instablity

Helen Knowles

Cellular & molecular mechanisms driving hypoxic amplification of osteoclastic bone resorption & identifying pathways regulating pathological bone resorption in rheumatoid arthritis

Michael Kohl

Encoding information in neural circuits

Skirmantas Kriaucionis

Epigenetic Mechanisms

Morten Kringelbach

Pleasure networks in the human brain

Jennifer J Kurinczuk

National Perinatal Epidemiology Unit; maternal and child health research

Dominic Kwiatkowski

Genomics and Global Health

Nick La Thangue

Cancer Biology

Nick Lakin

Detection, Signalling and Repair of DNA Damage

Sallie Lamb

Trauma Rehabilitation

Karri Lamsa

Plasticity in identified inhibitory circuits in the brain

Martin J Landray

Clinical Trial Service Unit

Bethan Lang

Autoantibodies in neurological diseases

Daniel Lasserson

My research looks at ways to reduce cardiovascular events in general practice. This is important because stroke and heart disease are the commonest causes of death and chronic disease burden. My research projects are in two major areas – stroke prevention and chronic kidney disease.

Jennifer Lau

Child and Adolescent Mood and Anxiety Problems

Susan Lea

Host-pathogen interactions including the Complement system, bacterial adhesion, type III and tat secretion systems and picornaviral-receptor interactions.

Simon Leedham

Homeostatic cell-signaling pathways that control intestinal stem cells and the dysregulation of these pathways in carcinogenesis.

Paul Leeson

Cardiovascular Imaging and Early Development of Cardiovascular Disease

Petros Ligoxygakis

Drosophila as a model to study innate immunity

Cecilia Lindgren

The genetics of obesity

Ji-Long Liu

Metabolic cell biology: CTP synthase, Cytoophidia, Cancer biology and CRISPR

Louise Locock

Interested in projects using qualitative research methods to understand health and illness experiences, and the use of these experiences to develop more patient-centred policy and practice, including service improvement and commissioning decisions. Current D Phils I am supervising focus on patient-centred care, use of personal health narratives for peer support and understanding healthy lifestyle choices.

Xin Lu

Tumour Supression

Kerstin Luhn

Immune regulation and innate immune responses in Dengue and other viral infections

Raashid Luqmani

Assessment and biology of systemic vasculitis

Valentine Macaulay

IGF Group

Clare Mackay

Using imaging to study psychiatric and neurodegenerative diseases

Peter Magill

Parkinson's disease. Interactions within and between the basal ganglia and thalamocortical circuits in function and dysfunction

Louis Mahadevan

Kinase cascades targeted to transcription factors and nucleosomal proteins involved in gene induction

Kamal R. Mahtani

My research primarily focuses on chronic disease, specifically in the areas of cardiovascular and musculoskeletal medicine. I am also interested in novel interventions to improve chronic disease management.

Martin Maiden

The interaction of molecular epidemiology, population biology and public health for bacterial pathogens

Julie Makani

Tropical Medicine & Global Health and Genetics & Genomics

Sue Mallett

My research is to design and analyse diagnostic and prognostic studies, including ongoing clinical trials and methodological work.

Kevin Maloy

Host-pathogen interactions in the intestine and their impact on intestinal inflammation

Erika J Mancini

Chromatin Remodeling and Transcriptional Regulation

Jonathan Marchini

Statistical and Computational Genetics

Ana Marques

Molecular mechanism of noncoding RNA function and contribution to disease

Brian Marsden

Protein Science and Structural Biology

Kevin Marsh

KEMRI Wellcome Collaborative Research programme

Maryanne Martin

Individual differences, psychosomatic illness, anxiety, economic decision making, cognitive processing, and handedness.

Mark McCarthy

The Genetics of Type-2 Diabetes & Related Traits

Rose McGready

Malaria in pregnancy

Peter McHugh

DNA damage and repair group

Gillies McKenna

Molecular Resistance to Treatments

Sylvia McLain

Structural and dynamical investigations of peptides, lipids and membranes from the atomic scale to the nanoscale

Richard McManus

My research interests include cardiovascular disease and its prevention, particularly the management of hypertension in primary care. I currently lead programmes of research around self-monitoring of blood pressure in both hypertension and pregnancy and welcome students wishing to base projects in these areas.

Andrew J McMichael

Antiviral Immunity, HIV

Helen McShane

Cellular Immunology and Vaccine Development

Gil McVean

Population and Evolutionary Genetics

Enda McVeigh

Infertility and laparoscopic surgery with a special interest in endometriosis

Adam Mead

Leukaemia Stem Cell Biology

Jane Mellor

Chromatin remodeling and gene regulation in simple eukaryotes

Sharon Mickan

Director MSc Evidence-Based Health Care

Kim Midwood

'The Danger Theory: understanding how the extracellular matrix controls immunity

Gero Miesenboeck

Our interests lie at the interface between cellular and systems neuroscience: we aim to understand how excitable cells are arranged into functional circuits, and how the operation of these circuits informs behaviour.

Karla Miller

Development of Magnetic Resonance Imaging (MRI) techniques for brain imaging

Tom Milne

Epigenetic control of gene expression in leukemia and haematopoiesis

Kalim Mir

Nanogenomics

David R Mole

Oxygen Sensing Group

Claudia Monaco

What is the best way to target inflammation in atherosclerosis?

Andrew P Morris

Genetic and Genomic Epidemiology Unit

Karl Morten

Mitochondrial Dysfunction, Therapeutics & Nanomedicine

Richard F Mott

Bioinformatics

Chris Murphy

Transcriptional, microRNA and epigenetic regulation of cartilage; Cartilage repair and stem cells

Michael Murphy

Childhood Cancer Research

Robin Murphy

Learning, Memory and Cognition

Shona Murphy

Regulation of expression of human genes.

David Murray

Biomechanical and clinical studies related to the knee and hip; biomechanical studies use anatomical, computer modelling, gait analysis and x-ray techniques to study normal, diseased and replaced joints; knee kinematics; methods to predict and prevent failure in joint replacements; Patient-based scores; development of new implants and surgical techniques

Ruth Muschel

Research group interested in the mechanisms underlying the development of metastasis.

Simon Myers

Recombination and Statistical Genetics

Saul Myerson

The Use of Cardiovascular Magnetic Resonance to guide prognosis and clinical management in cardiac valve disease

Jagdeep Nanchahal

Developing therapies for fibrosis and accelerating fracture healing

Kim Nasmyth

Chromosome Segregation During Mitosis and Meiosis

Kate Nation

Development & Disorders

Claus Nerlov

Hematopoietic stem cell maintenance and fate specification

Stefan Neubauer

The Role of Cardiac Energetics in Ischaemia and Heart Failure/Development and Application of Magnetic Resonance Techniques for Phenotyping of Cardiovascular Disease

Chris I Newbold

Molecular Parasitology, Malaria

Simon Newstead

Structural and Functional Studies of Membrane Proteins

Charles Newton

Neurodevelopmental Disorders, including Autistic Spectrum Disorders, Epilepsy and Sickle Cell Disease

Paul Newton

Infectious Disease and Nutrition in Laos

Kia (Anna Christina) Nobre

Neural systems and mechanisms for adaptive dynamic regulation of cognition in the human brain

Chris Norbury

Studying the involvement of post-transcriptional regulation of gene expression in cancer cell biology

Francois H Nosten

Shoklo Malaria research Unit

Bela Novak

Dynamics of molecular regulatory networks

Chris A O'Callaghan

Innate Immunity

Graham S Ogg

Cutaneous Immunology, Allergy, Dermatology, Viral infections and the skin, Innate and adaptive immune responses, Role of epithelium in immunity.

Peter Oliver

Outreach Some of my research programme examines the mechanisms that underlie the disrupted sleep patterns that are commonly observed neurological disorders, from Parkinson’s disease to schizophrenia. Although we all sleep every day, many of the concepts are misunderstood and the importance of having a good night’s sleep and the role of sleep in disease is often overlooked. Since 2011 I have been exploring new ways to present sleep and circadian rhythm research to the public. I began by speaking at Cafe Scientifique groups around Oxfordshire and in the city, which lead to further invites to talk at similar events around the country. I am also a keen musician, and in 2013 I was invited to lecture at the Oxford May Music Festival (Hollywell Music Rooms) where I used live drums to help illustrate some of the concepts involved. More recently I have been involved in two quite different public science events, Science Slam (Old Fire Station, Oxford October 2013) and Bright Club (Jericho Tavern, Oxford, March 2014) – both sell-outs - where a short entertaining set is required from several scientists in one night. In addition, I was selected as one of the scientists from over a hundred candidates to work with professional animators on new visual art pieces for the public. The project, entitled ‘Silent Signal’ has involved an R&D process with the animators and further selection of the proposals that will become part of a Large Arts Award submission to the Wellcome Trust. I have been working with award-winning animator Ellie Land on a piece named ‘Sleepless’ that is inspired by the concepts of synchrony and desynchrony; we will be discussing the creative process further as part of a panel at the Open City Docs Film Festival in London in June 2014. More info on the MRC FGU Outreach page .

Eric O'Neill

The main areas of interest in our lab are cell signalling and stem cells and cancer stem-like cells.

Udo Oppermann

Production, purification, functional characterization and structure determination of human metabolic enzymes of medical interest

Katharine Owen

Genetics of Type 2 Diabetes & Monogenic Diabetes

Ray Owens

Development and application of high throughput methods for molecular biology, protein purification and protein crystallization.

Jacqueline Palace

1. Clinical imaging research: neuroinflammatory disease (eg multiple sclerosis and neuromyelitis optica. 2. Clinical neuroimmunology: neuroinflammatory (eg ms) and antibody mediated neurological diseases eg myasthenia gravis and neuromyelitis optica? 3. Assessing utility of potential drugs for treatment of patients with abnormal AChR ion channel kinetics. 4. Neuro-ophthalmology: neuroinflammatory diseases (eg ms and neuromyelitis optica). 5. Neuro-genetics: neuroinflammatory conditions and diseases of the neuromuscular junction (eg myasthenia gravis). 6. Epidemiology of multiple sclerosis and neuromyelitis optica. 7. Clinical Chemistry: biomarkers of neuroinflammatory disease

Hemant Pandit

Assessment of knee kinematics, unicompartmental knee replacements (UKRs), metal-on-metal hip resurfacings, outcome assessment, and clinical trials of various interventions for OA.

Aris Papageorghiou

Maternal health, fetal growth, preterm delivery and newborn nutritional status

Rebecca Park

Social cognitive, emotional and reward processes in eating disorders

Brian Parkinson

Social Psychology

John Parrington

Molecular basis of egg activation. Role of phospholipase C enzymes in sperm. Calcium signalling and early embryogenesis. In vivo gene transfer into the testis and sperm. Identification and characterisation of the NAADP receptor. Molecular components of calcium signalling in sea urchin gametes

Roger Patient

Programming blood and the cardiovascular system

Kyle Pattinson

Functional MRI of Respiratory Control

Catherine Pears

The role of kinases in the choice of cell fate

Sarah Pendlebury

Cognitive deficits associated with strokes

Rafael Perera

I am a University Lecturer in Medical Statistics, and the Department's Head of Statistics. My general interests include: monitoring in primary care, meta-analysis methods, methodology for studying infectious diseases in children, and assessing complex interventions.

Richard Peto

Clinical Trial Service Unit

Francesco Pezzella

Angiogenesis, non angiogenesis, molecular analysis, gene expression profile, lung cancer

Rodney E Phillips

Antiviral Immunity, HIV

Fran Platt

Glycosphingolipids in health and disease.

Rutger Ploeg

Clinical, translational & experimental research in organ donation and transplantation and focus on mechanisms of injury & repair relevant to enhance donor organ quality, reduce ischaemia-reperfusion injury, improve preservation and allow regeneration after transplantation to increase allograft function and survival.

Kim Plunkett

Linguistics & Cognitive Development

Andrew Pollard

Adult and Paediatric Vaccinology and Paediatric Infection and Immunity

Patrick Pollard

Cell and Molecular Biology

Catherine Porcher

Transcriptional control of haemopoietic stem cell specification and differentiation

Mason A Porter

Statistical and nonlinear physics and their application to the physical, engineering, social, and biological sciences

Joanna Poulton

Mitichondrial Genetics

Fiona Powrie

Innate and adaptive immune pathways that control intestinal homeostasis and their breakdown in inflammatory bowel disease.

Andrew Price

Basic science and clinical programme of research in the understanding of cartilage damage, early arthritis and biological repair processes; clinical trials to study treatment of osteoarthritis in cartilage damage

Richard Price

Infectous Disease, Malaria

Nicholas Proudfoot

Interconnecting transcription and RNA processing in eukaryotes

Chris W Pugh

The Nephrology Oxygen Sensing Group

Maria A Quigley

National Perinatal Epidemiology Unit; maternal and child health research

Terry Rabbitts

Modelling consequences of chromosomal translocations in cancer and methods for protein-protein interaction inhibitor development

Jordan Raff

Centrioles and centrosome function.

Ioannis Ragoussis

Genomics: MicroRNAs in Disease

Najib Rahman

Pleural disease

Reshma Ramracheya

Cell and Molecular Biology

Peter J Ratcliffe

Hypoxia Biology Group

Christina Redfield

NMR studies of protein structure, function, folding and dynamics

Charles Redwood

Regulation on cardiac and skeletal muscle contractility

Jan Rehwinkel

Nucleic Acid Sensing by Innate Immune Receptors

Peter Robbins

Human Physiology: Effects of hypoxia and exercise on respiratory, cardiovascular and metabolic function

David Roberts

Erythropoiesis / Regulatory T cells in Bone Marrow Transplantation / Malaria Pathogenesis

Irene Roberts

The impact of trisomy 21 on haematopoiesis and leukaemia susceptibility.

Liz Robertson

Cell interactions underlying mammalian development and immune recognition.

Carol Robinson

Use of mass spectrometry to probe large intact protein assemblies

Matthew Robson

Cardiac MRI technique development; High and ultra-high field Cardiac MRI, High and ultra-high field Cardiac MRS

Patrik Rorsman

Diabetes, Insulin secretion

Peter Rose

Cancer survivors in primary care

Peter Rothwell

Stroke Prevention Research Unit

Sarah L Rowland-Jones

Immunity to HIV infection

Matthew Rushworth

Neural mechanisms of decision making and action selection

Angela Russell

Medicinal Chemistry

Andy Ryan

Lung cancer translational science

Sara Ryan

My research interests are around disability (particularly learning disability and autism), qualitative research and health experiences. I'm also interested in exploring ways of including people who are 'seldom heard' in research.

Afsie Sabokbar

Cellular mechanisms involved in the patho-physiology of various osteolytic diseases such as osteoporosis, osteoarthritis, rheumatoid arthritis, aseptic loosening, Paget's disease, cancer-induced bone metastases and Charcot neuro-arthropathy

Mark Sansom

Ion channels and membrane proteins - simulations, modelling & bioinformatics

Ian Sargent

Pre-eclampsia, Oxford Pregnancy Biobank, cellular micro and nanoparticles in pre-eclampsia, reproductive immunology, human embryo development

Quentin Sattentau

Retroviral Immunology.

Tatjana Sauka-Spengler

Genetics and Genomics

Gaia Scerif

Attention, Brain & Cognitive Development

Jurgen Schneider

Development of fast cardiac MRI techniques at ultra-high fields

Jason Schnell

Structure and regulation of ion channels and membrane-bound receptors

Anna Schuh

Genetics and Genomics

Len Seymour

Medicinal Virology

Ricky Sharma

Translation of biochemical knowledge of DNA adducts and excision repair to the prevention and treatment of cancer.

Trevor Sharp

Pharmacology and physiology of brain 5-HT neurones. Neuroadaptive processes associated with antidepressant treatment. Development of pharmacological strategies to improve the treatment of mood disorder.

Michael Sharpe

Psychological and psychiatric aspects of medical illness and practice

Alison Shaw

Ethnicity and social research in health

Mark Sheehan

Bioethics

David Sherratt

Our research is aimed at understanding how DNA replication, recombination and chromosome segregation shape bacterial chromosome organization in the context of the living cell.

Nicola Sibson

Imaging the microenvironment in brain metastasis

Christian Siebold

Hedgehog Signalling Group

Alison Simmons

Innate immunity in infectious and inflammatory disease

Katja Simon

Cell death and Autophagy in the Immune and Hematopoietic System

Rebeccah Slater

Paediatric Neuroscience: understanding the development of pain perception in human infants

Nicola Smart

Developmental Biology and Regenerative Medicine

Stephen Smith

Development of mathematical and computational tools for the analysis of brain imaging data

Hannah Smithson

Vision Science

Sarah Snelling

Role of Dickkopf-3 in the homeostasis and catabolism of cartilage in OA

Bob W Snow

Malaria Public Health & Epidemiology Group

Charles Spence

Applied cognitive psychology, Consumer psychology, Sensory marketing, Multisensory perception

Chris Spencer

Genetics and susceptibility to disease; using genetics to improve health and healthcare

Alan Stein

The development and mental health of children facing physical and psychological adversity

Richard Stevens

My current research interests include monitoring chronic diseases, especially diabetes and hypertension, and clinical prediction rules, especially risk scores. My publications, listed on my webpage at the department of primary care health sciences, give the best overview of my research.

Mark Stokes

The role of selective attention in perception, working memory and flexible decision-making and how these core cognitive functions are integrated for goal-directed adaptive behaviour.

Alan Storey

Cell Death Regulation Group

John Stradling

Obstructive sleep apnoea

Simon Stringer

Theoretical neuroscience and artificial intelligence

David Stuart

Viruses, Viral proteins and Cell surface receptors

Peter Sullivan

Nutrition and neurodevelopment in Cerebral Plasy

Christopher Summerfield

Neural and computational bases of human decision-making

Pawel Swietach

Myocardial Biology and Integrated Physiology

Francis Szele

Adult brain stem cells: from mechanisms to disease

Kevin Talbot

Motor Neuron Diseases

Paolo Tammaro

Determining the molecular mechanisms that underlie the function of vascular ion channels and identifying new ion channel targets and specific drug compounds with the goal of modulating blood vessel function for therapeutic benefit.

Christoph Tang

Pathogenesis and Prevention of Bacterial Meningitis

Madalena Tarsounas

How homologous recombination (HR), the major error-free pathway for DNA repair in mammalian cells, regulates telomeres and acts to prevent genomic instability, the underlying mechanism of many cancers.

Derek Terrar

Influence of drugs on cardiac muscle contraction (including the possible role of cyclic ADP ribose and related substances on excitation-contraction coupling) Pacemaker mechanisms and their regulation in the sino-atrial node Mechanisms of action of drugs used to treat cardiac arrhythmias (with particular reference to potassium channels and their cellular regulation) Mechanisms by which general anaesthetics exert harmful effects on the heart.

Rajesh V Thakker

Molecular basis of endocrine and renal tubular disorders

Matthew Thompson

My interests focus on three main areas: childhood illness, diagnostic tests, and infectious diseases. Methods I have used include evidence syntheses, cohort studies, diagnostic accuracy studies, qualitative studies and trials of interventions. I have had great success with Masters and GP academic fellows in the past in terms of publication output and promoting their careers.

Ian Tomlinson

Molecular and Population Genetics of Cancer

Alain R Townsend

Iron Metabolism and Immunology

Irene Tracey

1. Understanding the neural basis of pain perception and analgesia 2. Understanding the neural basis of consciousness

Ruth Travis

Clinical Epidemiology

Linda Troeberg

Identifying mechanisms regulating turnover of the extracellular matrix, with a view to developing therapies for degradative diseases such as osteoarthritis.

Stephen Tucker

Ion channel structure and function

Elizabeth Tunbridge

The role of catechol-O-methyltransferase in normal brain function and its dysfunction in psychiatric disorders.

Martin Turner

Biomarkers and pathogenesis in motor neuron disease (ALS)

Irina Udalova

Genomic and epigenetic control of inflammation: identification of key master regulators

Holm Uhlig

Mucosal Immunity and Inflammatory Bowel Disease

Ioannis Vakonakis

Structural studies of large assemblies in malaria cytoadherence and centriole duplication

Jose M Valderas

Main potential areas of interest at present are clinical applications of Patient Reported Outcome and Experiences Measures (PROMs and PREMs), the evaluation of quality and safety improvement interventions.

Katherine Vallis

Development of novel anti-cancer radiopharmaceuticals.

Anton van der Merwe

Molecular analysis of T and NK cell recognition.

Lidia Vasilieva

Post-transcriptional regulation of gene expression in eukaryotes

Manu Vatish

Senior Fellow in Obstetrics and Gynaecology

Richard Vaughan-Jones

Intracellular pH in heart: regulation and function

David Vaux

Human disease and proteins.

Jose Villar

INTERGROWTH-21st Project Fetal and neonatal growth

Angela Vincent

Identification and investigation of autoantibodies to muscle and neuronal proteins in neurological diseases of adults and children

Tonia Vincent

Molecular Pathogenesis of Osteoarthritis

Tim Vogels

Theoretical and Computational Neuroscience

Boris Vojnovic

Development of instrumentation to address specific biological hypotheses, primarily involving imaging and image processing.

Emanuela Volpi

Molecular Cytogenetics

Frank von Delft

Crystallography

Frank Vreede

Regulation of influenza A virus replication and transcription

Paresh Vyas

Normal and Leukaemic stem/progenitor cell biology

Vladyslav Vyazovskiy

Investigating mechanisms and physiological significance of cortical network activity during waking and sleep using in vivo rodent models

Scott Waddell

Neural Mechanisms of Memory, Motivation and Behavioural Control

George Wadhams

In vivo quantitative analysis of natural and synthetic bacterial signalling pathways

Sten Eirik Waelgaard Jacobsen

Delineation of cellular and molecular pathways of normal and leukemic haematopoietic stem cell fate decisions

Herman Waldmann

Regulatory T-cells, nutrient sensing, mTOR, proteomics of regulatory T-cells

Mark Wallace

Understanding the assembly and function of membrane-proteins using techniques capable of observing individual molecules

Mark Walton

Neuropsychology and neurochemistry of decision making

Hugh Watkins

Molecular Genetics and Molecular Biology of the Heart Muscle Disease/Molecular Genetics of Complex Cardiovascular Phenotypes

Kate Watkins

Sensorimotor networks underlying speech production and perception; Stuttering; Developmental disorders of speech and language; brain imaging, brain stimulation. Development and plasticity.

Suzanne Watt

Improving bone marrow transplants- through better engraftment / Stem/progenitor cell expansion and reprogramming / Revascularising tissues for tissue repair

Anthony Watts

Resolving structural details of membrane peptides and proteins at high resolution

Caleb Webber

Neurological Disease Genomics

Premila Webster

Urbanisation and chronic disease and Global Health

Dagan Wells

Molecular genetic processes underlying gametogenesis and preimplantation development

Matthew Whitby

Genetic recombination and DNA repair in eukaryotes

Nicholas J White

Tropical Medicine, Infectious Disease and Drug Discovery

Andrew Wilkie

Skulls, limbs, and sperm: common themes in malformation

Keith Willett

Care of pateinets with multiple trauma fractures, mainly studying fractures in the elderly, limb fracture surgery, fracture biomechanics, accident prevention and clinical outcome studies of orthopaedic trauma surgery techniques

Richard Williams

Targeting disease pathways in rheumatoid arthritis

Suzannah Willliams

The role of the oocyte in regulating fertility

Bridget Wills

Tropical Medicine

Kathryn Wood

Transplant rejection and tolerance

Alison Woollard

Molecular mechanisms controlling cell fate determination and cell proliferation during C. elegans development

Mark Woolrich

Development of mathematical and computational tools for the analysis of brain imaging data

Paul Wordsworth

Genetics of inflammatory arthritis e.g. rheumatoid arthritis & ankylosing spondylitis; heritable disorders of the skeleton &soft tissues, inflammatory arthritis and auto immune connective tissue diseases

Mark Wormald

NMR studies of oligosaccharides and glycoprotein conformation and dynamics

Christopher Yau

Computational statistical methods for applications in genetics and genomics

Nicholas Yeung

Human cognitive neuroscience: attention and control; decision making and learning

Wyatt Yue

Protein Science and Structural Biology

Manuela Zaccolo

Intracellular signal transduction by cyclic nucleotides. Mechanisms, regulation, signalling networks and role in disease.

Sue Ziebland

Sue is a medical sociologist with particular interest in how people use the internet in relation to their health. While specialising in qualitative research she also has an interest in mixed methods studies

Nicole Zitzmann

Hepatitis - Development of Antiviral Strategies

Krina Zondervan

Genetic and environmental background of endometriosis and related conditions