Microbiology, Infection and Tropical Medicine

Oxford's contribution to infectious disease has been enormous. Penicillin and the related cephalosporin antibiotics were discovered here. More recently Oxford has played a key role in the introduction of artemisinin-related drugs for malaria and in the development of new vaccines for bacterial meningitis and tuberculosis.

Oxford is rated the top University in the UK in the area of Infection and Immunity. It has a strong core of microbiological expertise ranging from fundamental through to translational research and clinical trials. Areas of strength in basic research include microbial structure-function relationships, aspects of viral, bacterial and parasite pathogenesis, and interaction of pathogens with the immune system including immune evasion strategies. Areas of strength in translational research include study of the mucosal microbiota in health and disease, development of vaccines against parasitic, bacterial and viral pathogens and screening for novel drugs against viral infections. Much translation research is done in Oxford’s Tropical Medicine research units in Africa and Asia. Microbiology research is performed in a number of University Departments including the Nuffield Department of Clinical Medicine, Sir William Dunn School of Pathology, Paediatrics and Biochemistry. Institutes include the Weatherall Institute for Molecular Medicine and the Jenner Institute and the Institute for Vaccine Design

Structured DPhil Programmes

MSc Taught Programmes

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Supervisors in Microbiology, Infection and Tropical Medicine

Brian J Angus

Malaria, HIV and Melioidosis

Judy Armitage

Flagellar rotation and intracellular signalling pathways controlling bacterial chemotaxis

Ellie Barnes

Human Chronic Viruses

James Berkley

Global childhood infection & immunity

Ben Berks

Bacterial protein transport and bacterial energy metabolism

Terry Butters

Chemistry and biology of imino sugar inhibitors

Climent Casals-Pascual

A systems approach to malaria

Vincenzo Cerundolo

Vaccination, cancer immunology and NKT cell function

Richard, J Cornall

Autoimmunity and Immune Regulation Group

Derrick Crook

Infectious Disease

Nick PJ Day

Mahidol-Oxford Tropical Medicine Research Unit

Tao Dong

Anti-viral T cell response

Lucy Dorrell

Immune modulation in HIV infection

Simon J Draper

Blood-Stage Malaria Vaccine Group

Mike English

Improving delivery of evidence based care for severely ill children

Jeremy Farrar

Oxford University Clinical Research Unit, Viet Nam

Ervin Fodor

Influenza virus replication at the molecular level.

John Frater

HIV Infection

Sarah C Gilbert

Vaccine Development

Geraldine Gillespie

The molecular and epigenetic biology of NK cells

Eva Gluenz

Cell biology of Leishmania; role of the flagellum in host-parasite interactions

Philip Goulder

Paediatric HIV T cell immunology

Jonathan M Grimes

dsRNA viruses

Kay Grunewald

Structural cell biology of virus infection

Keith Gull

Aspects of the pathogenicity of African trypanosomes and inherited ciliary diseases of humans.

Tomas Hanke

HIV-1 Vaccine Development Group

Matt Higgins

Structural studies of the malaria parasite

Adrian VS Hill

Jenner Institute / Infectious Diseases / Malaria Vaccine Trials

Ling-Pei Ho

The immunology of respiratory infections

Jonathan Hodgkin

Genetics of nematode immunity and development

Peter Horby

Oxford University Clinical Research Unit, Viet Nam

Mark Howarth

Bionanotechnology and its application to Cancer

David G Jackson

Lymphatics and cell trafficking

William James

HIV-Macrophage interactions and stem cell technology

Dominic Kelly

Paediatric vaccine immunology with particular interest in B-cell responses. Epidemiology of invasive bacterial disease and pneumonia in childhood.

Paul Klenerman

Antiviral immunity

Julian C Knight

Functional genomics of inflammation and immunity

Dominic Kwiatkowski

Genomics and Global Health

Susan Lea

Host-pathogen interactions including the Complement system, bacterial adhesion, type III and tat secretion systems and picornaviral-receptor interactions.

Niklas Lindegardh

Clinical Pharmacology Laboratory MORU

Kerstin Luhn

Immune regulation and innate immune responses in Dengue and other viral infections

Julie Makani

Tropical Medicine & Global Health and Genetics & Genomics

Kevin Maloy

Host-pathogen interactions in the intestine and their impact on intestinal inflammation

Kevin Marsh

KEMRI Wellcome Collaborative Research programme

Rose McGready

Malaria in pregnancy

Andrew J McMichael

Antiviral Immunity, HIV

Helen McShane

Cellular Immunology and Vaccine Development

Kim Midwood

'The Danger Theory: understanding how the extracellular matrix controls immunity

Chris I Newbold

Molecular Parasitology, Malaria

Paul Newton

Infectious Disease and Nutrition in Laos

Francois H Nosten

Shoklo Malaria research Unit

Graham S Ogg

Cutaneous Immunology, Allergy, Dermatology, Viral infections and the skin, Innate and adaptive immune responses, Role of epithelium in immunity.

Rodney E Phillips

Antiviral Immunity, HIV

Fran Platt

Glycosphingolipids in health and disease.

Andrew Pollard

Adult and Paediatric Vaccinology and Paediatric Infection and Immunity

Fiona Powrie

Innate and adaptive immune pathways that control intestinal homeostasis and their breakdown in inflammatory bowel disease.

Richard Price

Infectous Disease, Malaria

Jan Rehwinkel

Nucleic Acid Sensing by Innate Immune Receptors

David Roberts

Erythropoiesis / Regulatory T cells in Bone Marrow Transplantation / Malaria Pathogenesis

Sarah L Rowland-Jones

Immunity to HIV infection

Mark Sansom

Ion channels and membrane proteins - simulations, modelling & bioinformatics

Quentin Sattentau

Retroviral Immunology.

Chris Scanlan

Carbohydrate-based vaccine design for HIV/AIDS

Anthony Scott

Invasive Bacterial Diseases Group

Alison Simmons

Innate immunity in infectious and inflammatory disease

Steven Sinkins

Genetics and Genomics

Bob W Snow

Malaria Public Health & Epidemiology Group

Christoph Tang

Pathogenesis and Prevention of Bacterial Meningitis

Matthew Thompson

My interests focus on three main areas: childhood illness, diagnostic tests, and infectious diseases. Methods I have used include evidence syntheses, cohort studies, diagnostic accuracy studies, qualitative studies and trials of interventions. I have had great success with Masters and GP academic fellows in the past in terms of publication output and promoting their careers.

Alain R Townsend

Iron Metabolism and Immunology

Holm Uhlig

Mucosal Immunity and Inflammatory Bowel Disease

Ioannis Vakonakis

Structural studies of large assemblies in malaria cytoadherence and centriole duplication

Frank Vreede

Regulation of influenza A virus replication and transcription

Nicholas J White

Tropical Medicine, Infectious Disease and Drug Discovery

Thomas N Williams

Host Genetics: Haemoglobinopathies and Infectious Disease

Bridget Wills

Tropical Medicine

Nicole Zitzmann

Hepatitis - Development of Antiviral Strategies

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